ZFIN ID: ZDB-GENE-990415-58
Gene Name: eph-like kinase 1
Gene Symbol: ek1    Nomenclature History

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Previous Names: epha4d (1), etID309879.24 (1), rtk7, zek1, zgc:100780

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 24 Mapping Details/Browsers
Description: Predicted to have GPI-linked ephrin receptor activity and transmembrane-ephrin receptor activity. Predicted to be involved in several processes, including axon development; regulation of cytoskeleton organization; and regulation of focal adhesion assembly. Predicted to localize to several cellular components, including early endosome; integral component of plasma membrane; and neuron projection. Is expressed in central nervous system and neural tube. Orthologous to human EPHA1 (EPH receptor A1).
Genome Resources: Alliance (1),  Gene:30311 (1),  Ensembl(GRCz11):ENSDARG00000020080 (2)
GENE EXPRESSION
All Expression Data: 7 figures from 2 publications
Directly Submitted Expression Data: 6 figures (10 images) from Thisse et al., 2005 [eu792]
Wild-type Stages, Structures: Segmentation:1-4 somites (10.33h-11.66h) to Hatching:Long-pec (48.0h-60.0h)
 
High Throughput Expression: GEO (1) Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la022963Tg Transgenic Insertion Unknown Unknown DNA
la028629Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la028630Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa8415 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa8869 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa24519 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa37911 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa37912 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa39457 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa44161 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH ek1 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH ek1 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process cell migration (more)
    Cellular Component early endosome (more)
    Molecular Function GPI-linked ephrin receptor activity (more)
    GO Terms (all 31)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA ek1-201 (1)    Ensembl 4537
    ek1-202 (1)    Ensembl 1968
    ncRNA ek1-003 (1)    Ensembl 475
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM ek1 No data available
    MARKER RELATIONSHIPS
    ek1 Contained in: [BAC] CH211-260D11 (1), DKEY-39F23 (1) (order this)
    ek1 Encodes: [EST] eu792 (1)
    [cDNA] MGC:100780 (1), MGC:193628 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_131095 (1) 4577 nt
    Genomic GenBank:CR352262 (1) 223466 nt Blast at MegaBLAST
    Polypeptide UniProtKB:B3DGS3 (1) 981 aa
    Sequence Information (all 30)
    ORTHOLOGY for ek1 ( Chr: 24 )
    CITATIONS (32)