ZFIN ID: ZDB-GENE-990415-48
Gene Name: distal-less homeobox 1a
Gene Symbol: dlx1a    Nomenclature History

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Previous Names: dlx1, zgc:111939

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 9 Mapping Details/Browsers
Description: Predicted to have DNA-binding transcription factor activity and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in cartilage development and embryonic viscerocranium morphogenesis. Predicted to localize to nucleus. Is expressed in brain; head; and ventricular zone. Orthologous to human DLX1 (distal-less homeobox 1).
Genome Resources: Alliance (1),  Gene:30568 (1),  Ensembl(GRCz11):ENSDARG00000013125 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa13132 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-dlx1a N/A 3
    DISEASE ASSOCIATED WITH dlx1a HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH dlx1a VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process cartilage development (more)
    Cellular Component nucleus (more)
    Molecular Function DNA binding (more)
    GO Terms (all 16)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    Browsers: NCBI
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM dlx1a
    Construct Regulatory Regions Coding Sequences Species Tg Lines Publications
    Tg(dlx1aIG:GFP) dlx1adlx2a GFP Danio rerio 2 4
    Tg(dlx1aURE2:GFP) dlx1adlx2a GFP Danio rerio 2 5
    MARKER RELATIONSHIPS
    dlx1a Contained in: [BAC] CH211-245G15 (1)
    dlx1a Encodes: [EST] eu593 (1)
    [cDNA] MGC:111939 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_131305 (1) 1211 nt
    Genomic GenBank:BX248116 (1) 161065 nt
    Select Tool
    Polypeptide UniProtKB:Q98875 (1) 252 aa
    Sequence Information (all 17)
    ORTHOLOGY for dlx1a ( Chr: 9 )
    CITATIONS (53)