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General Information
ZIRC
ZFIN ID: ZDB-GENE-990415-45
Gene Name: phospholipase A2, group IVAa (cytosolic, calcium-dependent)
Gene Symbol: pla2g4aa
Sequence Ontology ID : SO:0000704

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Previous Names: cpla2, pla2g4

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(Including Attributions)
Location: Chr: 2 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Exhibits phospholipase activity. Involved in inflammatory response to wounding; ovarian follicle development; and regulation of G1/S transition of mitotic cell cycle. Predicted to localize to the  ...
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la023497Tg Transgenic Insertion Unknown Unknown DNA
sa7312 Point Mutation Unknown Premature Stop ENU
sa39810 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Targeting reagents:
    PHENOTYPE
    Data: Fig. 4 from Naini et al., 2016
    Observed in:
    DISEASE ASSOCIATED WITH pla2g4aa HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    Gastrointestinal ulceration, recurrent, with dysfunctional platelets 618372
    Gastrointestinal ulceration, recurrent, with dysfunctional platelets 618372
    DISEASE ASSOCIATED WITH pla2g4aa VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process regulation of G1/S transition of mitotic cell cycle (more)
    Cellular Component cytoplasm (more)
    Molecular Function phospholipase activity (more)
    GO Terms (all 24)
    TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA pla2g4aa-201 (1) 2591
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM pla2g4aa
    MARKER RELATIONSHIPS
    pla2g4aaContained in: [BAC] CH73-86N6 (1) (order this), CH73-147D18 (1) (order this), CH73-156H13 (1) (order this)
    pla2g4aaEncodes: [cDNA] MGC:193527 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_131295 (1) 2592bp
    Genomic GenBank:CU570979 (1) 105710bp
    Select Tool
    Polypeptide UniProtKB:B3DFL0 (1) 741aa
    Sequence Clusters UniGene:20961 (1)
    Sequence Information (all 16)
    ORTHOLOGY for pla2g4aa (Chr: 2)
    CITATIONS (47)