Gene

hoxa11b

ID
ZDB-GENE-990415-4
Name
homeobox A11b
Symbol
hoxa11b Nomenclature History
Previous Names
  • Hoxa-11
  • hoxa11
  • im:7142641
Type
protein_coding_gene
Location
Chr: 16 Mapping Details/Browsers
Description
Predicted to have DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in anatomical structure development and regulation of transcription by RNA polymerase II. Predicted to localize to nucleus. Is expressed in several structures, including central nervous system; chondroblast; mesenchyme; pectoral fin bud; and pectoral fin field. Human ortholog(s) of this gene implicated in radioulnar synostosis. Orthologous to human HOXA11 (homeobox A11).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
14 figures from 6 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With hoxa11b Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Radioulnar synostosis with amegakaryocytic thrombocytopenia 1 605432
Associated With hoxa11b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR017970 Homeobox, conserved site
Domain IPR001356 Homeobox domain
Domain IPR020479 Homeobox domain, metazoa
Domain IPR021918 Domain of unknown function DUF3528, homeobox protein, eukaryotic
Homologous_superfamily IPR009057 Homeobox-like domain superfamily
Domain Details Per Protein
Protein Length Domain of unknown function DUF3528, homeobox protein, eukaryotic Homeobox, conserved site Homeobox domain Homeobox domain, metazoa Homeobox-like domain superfamily
UniProtKB:Q9DDU1 283
UniProtKB:B3DHW9 283
UniProtKB:F1RBM6 283
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations