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General Information
ZIRC
ZFIN ID: ZDB-GENE-990415-37
Gene Name: complement component c3a, duplicate 3
Gene Symbol: c3a.3
Sequence Ontology ID : SO:0001217

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Previous Names: C3-3 (1), c3.3 (1), c3c, unp301

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(Including Attributions)
Location: Chr: 1 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have endopeptidase inhibitor activity. Predicted to be involved in complement activation. Predicted to localize to the extracellular space. Human ortholog(s) of this gene implicated in  ...
GENE EXPRESSION
All Expression Data: 5 figures from 4 publications
Wild-type Stages, Structures: Hatching:Long-pec (48.0h-60.0h) to Adult (90d-730d, breeding adult)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa9572 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa12504 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa32793 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • zko1164a Indel Unknown Unknown CRISPR
    Targeting reagents:
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH c3a.3 HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    age related macular degeneration 9 {Macular degeneration, age-related, 9} 611378
    complement component 3 deficiency C3 deficiency 613779
    {Hemolytic uremic syndrome, atypical, susceptibility to, 5} 612925
    DISEASE ASSOCIATED WITH c3a.3 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process complement activation (more)
    Cellular Component extracellular region (more)
    Molecular Function endopeptidase inhibitor activity (more)
    GO Terms (all 4)
    TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA c3a.3-201 (1) 5209
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM c3a.3 No data available
    MARKER RELATIONSHIPS
    c3a.3 Contained in: [BAC] DKEY-121K17 (1) (order this)
    c3a.3 Has Artifact: [cDNA] MGC:103610 (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001037236 (1) 5165 bp
    Genomic GenBank:AL928676 (1) 176196 bp
    Select Tool
    Polypeptide UniProtKB:F1R9X9 (1) 1654 aa
    Sequence Clusters UniGene:88584 (1)
    Sequence Information (all 14)
    ORTHOLOGY for c3a.3 ( Chr: 1 )
    CITATIONS (30)