Gene

wnt8b

ID
ZDB-GENE-990415-279
Name
wingless-type MMTV integration site family, member 8b
Symbol
wnt8b Nomenclature History
Previous Names
None
Type
protein_coding_gene
Location
Chr: 13 Mapping Details/Browsers
Description
Predicted to have frizzled binding activity. Involved in several processes, including Wnt signaling pathway; animal organ development; and commissural neuron axon guidance. Predicted to localize to extracellular space. Human ortholog(s) of this gene implicated in Hirschsprung's disease. Is expressed in several structures, including anterior neural rod; brain; midbrain hindbrain boundary neural keel; midbrain hindbrain boundary neural rod; and neural plate. Orthologous to human WNT8B (Wnt family member 8B).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
45 figures from 27 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
8 figures from 5 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With wnt8b Human Ortholog
No data available
Associated With wnt8b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR018161 Wnt protein, conserved site
Family IPR005817 Wnt
Family IPR013301 Wnt-8 protein
Family IPR034311 Protein Wnt-8B
Homologous_superfamily IPR043158 Wnt, C-terminal domain
Domain Details Per Protein
Protein Length Protein Wnt-8B Wnt Wnt-8 protein Wnt, C-terminal domain Wnt protein, conserved site
UniProtKB:A0A0B5JKB4 358
UniProtKB:P51029 358
UniProtKB:B7ZD55 358
Transcripts
Genome Browsers
Interactions and Pathways
Antibodies
No data available
Plasmids
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations