ZFIN ID: ZDB-GENE-990415-243
Gene Name: retinoid x receptor, alpha b
Gene Symbol: rxrab    Nomenclature History

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Previous Names: rxra, rxrg, etID309731.5 (1), NR2B1-A (1), RXRalpha-A (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 5 Mapping Details/Browsers
Description: Exhibits nuclear receptor activity. Predicted to be involved in several processes, including regulation of transcription by RNA polymerase II; response to retinoic acid; and retinoic acid receptor signaling pathway. Predicted to localize to RNA polymerase II transcription regulator complex and nucleus. Is expressed in several structures, including cardiovascular system; retina; segmental plate; swim bladder bud; and tail bud. Human ortholog(s) of this gene implicated in pancreatic cancer. Orthologous to human RXRA (retinoid X receptor alpha).
Genome Resources: Alliance (1),  Gene:793011 (1),  Ensembl(GRCz11):ENSDARG00000035127 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa1205 Point Mutation Unknown Premature Stop ENU
sa11783 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa16874 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH rxrab HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH rxrab VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process positive regulation of transcription by RNA polymerase II (more)
    Cellular Component host cell nucleus (more)
    Molecular Function nuclear receptor activity (more)
    GO Terms (all 20)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA rxrab-201 (1)    Ensembl 1721
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    SignaFish
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM rxrab No data available
    MARKER RELATIONSHIPS
    rxrab Contained in: [BAC] CH73-262B19 (1)
    rxrab Encodes: [EST] u29894 (2)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_131153 (1) 1285 nt
    Genomic GenBank:FP016250 (1) 124349 nt
    Select Tool
    Polypeptide UniProtKB:F1RDN3 (1) 379 aa
    Sequence Information (all 16)
    ORTHOLOGY for rxrab ( Chr: 5 )
    CITATIONS (41)