ZFIN ID: ZDB-GENE-990415-238
Gene Name: retinal homeobox gene 3
Gene Symbol: rx3
Sequence Ontology ID : SO:0000704

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Previous Names: chk, chokh, eyes missing (1), eym (1)

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(Including Attributions)
Location: Chr: 21 Mapping Details/Browsers
GENE EXPRESSION
All Expression Data: 72 figures from 44 publications
Wild-type Stages, Structures: Gastrula:Shield (6.0h-8.0h) to Adult (90d-730d, breeding adult)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
hu499 Point Mutation Unknown Unknown ENU
ne2611 Point Mutation Exon 2 Missense ENU
rx3_unspecified Unspecified Unknown Unknown
s399 Point Mutation Unknown Premature Stop ENU
sa29528 Point Mutation Unknown Splice Site ENU
t25181 Point Mutation Unknown Missense ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • t25327 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • w29 Point Mutation Unknown Unknown ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Targeting reagents:
    PHENOTYPE
    Data: 20 figures from 10 publications
    Observed in:
    DISEASE ASSOCIATED WITH rx3 HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    isolated microphthalmia 3 Microphthalmia, isolated 3 611038
    microphthalmia Microphthalmia, isolated 3 611038
    DISEASE ASSOCIATED WITH rx3 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process adenohypophysis development (more)
    Cellular Component nucleus (more)
    Molecular Function DNA binding (more)
    GO Terms (all 15)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR001356 (1)
  • InterPro:IPR003654 (1)
  • InterPro:IPR009057 (1)
  • InterPro:IPR017970 (1)
  • PROSITE:PS00027 (1)
  • PROSITE:PS50071 (1)
  • PROSITE:PS50803 (1)
  • Pfam:PF00046 (1)
  • Pfam:PF03826 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA rx3-001 (1) 1411
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM rx3
    MARKER RELATIONSHIPS
    rx3Contained in: [BAC] CH211-233A1 (1) (order this)
    rx3Encodes: [cDNA] MGC:195183 (1), MGC:195186 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_131227 (1) 1322bp
    Genomic GenBank:BX248399 (1) 158884bp
    Select Tool
    Polypeptide UniProtKB:A8E7H4 (1) 292aa
    Sequence Clusters UniGene:540 (1)
    Sequence Information (all 17)
    OTHER rx3 GENE PAGES
  • Alliance (1)
  • Gene:30474 (1)
  • VEGA:OTTDARG00000018942 (1)
  • Ensembl(GRCz11):ENSDARG00000052893 (1)
  • ORTHOLOGY for rx3 (Chr: 21)
    CITATIONS (108)