ZFIN ID: ZDB-GENE-990415-238 |
Gene Name: | retinal homeobox gene 3 | ||||||
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Gene Symbol: | rx3 | ||||||
Sequence Ontology ID : | SO:0000704 | ||||||
Previous Names: | chk, chokh, eyes missing (1), eym (1) | ||||||
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Location: | Chr: 21 Mapping Details/Browsers |
All Expression Data: | 72 figures from 44 publications |
Wild-type Stages, Structures: | Gastrula:Shield (6.0h-8.0h) to Adult (90d-730d, breeding adult) |
anatomical structure, anterior neural plate, caudal hypothalamic zone, diencephalon![]() |
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Curated Microarray Expression: | GEO (1) |
Allele | Type | Localization | Consequence | Mutagen | Suppliers |
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hu499 | Point Mutation | Unknown | Unknown | ENU | |
ne2611 | Point Mutation | Exon 2 | Missense | ENU | |
rx3_unspecified | Unspecified | Unknown | Unknown | ||
s399 | Point Mutation | Unknown | Premature Stop | ENU | |
sa29528 | Point Mutation | Unknown | Splice Site | ENU | |
t25181 | Point Mutation | Unknown | Missense | ENU |
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t25327 | Point Mutation | Unknown | Premature Stop | ENU |
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w29 | Point Mutation | Unknown | Unknown | ENU |
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Targeting reagents: | MO1-rx3 (1), MO2-rx3 (1), MO3-rx3 (1) |
Data: | 18 figures from 9 publications |
Observed in: |
adenohypophysis, adenohypophysis development, camera-type eye morphogenesis, caudal hypothalamic zone anterior region![]() |
Disease Ontology Term | OMIM Term | OMIM Phenotype ID |
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isolated microphthalmia 3 | Microphthalmia, isolated 3 | 611038 |
microphthalmia | Microphthalmia, isolated 3 | 611038 |
Ontology | GO Term |
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Biological Process | adenohypophysis development (more) |
Cellular Component | nucleus (more) |
Molecular Function | DNA binding (more) |
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tg(rx3:kaede) |
rx3Contained in: | [BAC] CH211-233A1 (1) (order this) |
rx3Encodes: | [cDNA] MGC:195183 (1), MGC:195186 (1) |
Type | Accession # | Length (bp/aa) | Analysis |
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RNA | RefSeq:NM_131227 (1) | 1322bp |
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Genomic | GenBank:BX248399 (1) | 158884bp | |
Polypeptide | UniProtKB:A8E7H4 (1) | 292aa |
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Sequence Clusters | UniGene:540 (1) |
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