ZFIN ID: ZDB-GENE-990415-237
Gene Name: retinal homeobox gene 2
Gene Symbol: rx2
Sequence Ontology ID : SO:0000704

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Location: Chr: 2 Mapping Details/Browsers
AUTOMATED DESCRIPTION
Predicted to have DNA-binding activity transcription factor activity and sequence-specific DNA binding activity; involved in camera-type eye photoreceptor cell differentiation; predicted to localize  ...
GENE EXPRESSION
All Expression Data: 21 figures from 20 publications
Wild-type Stages, Structures: Gastrula:Bud (10.0h-10.33h) to Adult (90d-730d, breeding adult)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa31303 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Targeting reagents:
    PHENOTYPE
    Data: Fig. 6 from Nelson et al., 2009
    Observed in:
    DISEASE ASSOCIATED WITH rx2 HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    isolated microphthalmia 3 Microphthalmia, isolated 3 611038
    DISEASE ASSOCIATED WITH rx2 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process camera-type eye photoreceptor cell differentiation (more)
    Cellular Component nucleus (more)
    Molecular Function DNA binding (more)
    GO Terms (all 8)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR001356 (1)
  • InterPro:IPR003654 (1)
  • InterPro:IPR009057 (1)
  • InterPro:IPR017970 (1)
  • InterPro:IPR032967 (1)
  • PROSITE:PS00027 (1)
  • PROSITE:PS50071 (1)
  • PROSITE:PS50803 (1)
  • Pfam:PF00046 (1)
  • Pfam:PF03826 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA rx2-201 (1) 1489
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM rx2
    MARKER RELATIONSHIPS
    rx2Contained in: [BAC] CH73-332L5 (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_131226 (1) 1138bp
    Genomic GenBank:CU855756 (1) 106307bp
    Select Tool
    Polypeptide UniProtKB:F1QNV0 (1) 327aa
    Sequence Clusters UniGene:152552 (1)
    Sequence Information (all 15)
    OTHER rx2 GENE PAGES
  • Alliance (1)
  • Gene:30473 (1)
  • VEGA:OTTDARG00000034722 (1)
  • Ensembl(GRCz11):ENSDARG00000040321 (2)
  • ORTHOLOGY for rx2 (Chr: 2)
    CITATIONS (51)