ZFIN ID: ZDB-GENE-990415-206
Gene Name: pescadillo
Gene Symbol: pes    Nomenclature History

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Previous Name: etID309792.5 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 5 Mapping Details/Browsers
Description: Predicted to have ribonucleoprotein complex binding activity. Involved in exocrine pancreas development; oligodendrocyte differentiation; and regulation of cell cycle. Predicted to localize to PeBoW complex; nucleoplasm; and preribosome, large subunit precursor. Is expressed in several structures, including alar plate midbrain region; digestive system; liver primordium; musculature system; and nervous system. Used to study Shwachman-Diamond syndrome. Orthologous to human PES1 (pescadillo ribosomal biogenesis factor 1).
Genome Resources: Alliance (1),  Gene:30228 (1),  Ensembl(GRCz11):ENSDARG00000018902 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
hi2Tg Transgenic Insertion 5' UTR Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa6964 Point Mutation Unknown Splice Site ENU
    sa9660 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa16092 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa20356 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa26419 Point Mutation Unknown Splice Site ENU
    sa40366 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa45188 Point Mutation Unknown Splice Site ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • vu166 Point Mutation Unknown Premature Stop ENU
    Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-pes N/A 2
    DISEASE ASSOCIATED WITH pes HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH pes VIA EXPERIMENTAL MODELS
    Human Disease Fish Conditions Citations
    Shwachman-Diamond syndrome peshi2Tg/hi2Tg standard conditions Provost et al., 2012
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process exocrine pancreas development (more)
    Cellular Component nucleolus (more)
    Molecular Function ribonucleoprotein complex binding (more)
    GO Terms (all 13)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA pes-201 (1)    Ensembl 2485
    ncRNA pes-002 (1)    Ensembl 379
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM pes No data available
    MARKER RELATIONSHIPS
    pes Contained in: [BAC] CH73-135P21 (1), DKEYP-86G2 (1)
    pes Encodes: [cDNA] MGC:56654 (1), MGC:172160 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_131030 (1) 2422 nt
    Genomic GenBank:BX470167 (1) 189590 nt
    Select Tool
    Polypeptide UniProtKB:P79741 (1) 583 aa
    Sequence Information (all 19)
    ORTHOLOGY for pes ( Chr: 5 )
    CITATIONS (51)