ZFIN ID: ZDB-GENE-990415-183
Gene Name: notch 1b
Gene Symbol: notch1b

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Previous Names: etID309871.5 (1), wu:fc55e11

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(Including Attributions)
Location: Chr: 5 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 109 figures from 74 publications
Directly Submitted Expression Data: 7 figures (10 images) from Thisse et al., 2005 [eu523]
Wild-type Stages, Structures: Gastrula:Bud (10.0h-10.33h) to Adult (90d-730d, breeding adult)
  anatomical structure, artery, atrial endocardium distal region, atrioventricular canal (all 48) expand
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa1187 Point Mutation Unknown Splice Site ENU
sa11236 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa26616 Point Mutation Unknown Premature Stop ENU
    sa26617 Point Mutation Unknown Splice Site ENU
    Targeting reagents: MO1-notch1b (1), MO2-notch1b (1), MO3-notch1b (1), MO4-notch1b (1), MO5-notch1b (1) (all 7) expand
    PHENOTYPE
    Data: 9 figures from 7 publications
    Observed in: blood vessel morphogenesis, choroid plexus fourth ventricle, dorsal telencephalon radial glial cell, dorsal telencephalon ventricular zone (all 15) expand
    DISEASE ASSOCIATED WITH notch1b HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    Adams-Oliver syndrome Adams-Oliver syndrome 5 616028
    aortic valve stenosis Aortic valve disease 1 109730
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process dorsal aorta development (more)
    Cellular Component integral component of membrane (more)
    Molecular Function calcium ion binding (more)
    GO Terms (all 20)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000152 (1)
  • InterPro:IPR000742 (1)
  • InterPro:IPR000800 (1)
  • InterPro:IPR001881 (1)
  • InterPro:IPR002110 (1)
  • InterPro:IPR008297 (1)
  • InterPro:IPR009030 (1)
  • InterPro:IPR010660 (1)
  • InterPro:IPR011656 (1)
  • InterPro:IPR013032 (1)
  • InterPro:IPR018097 (1)
  • InterPro:IPR020683 (1)
  • InterPro:IPR022362 (1)
  • InterPro:IPR024600 (1)
  • PROSITE:PS00010 (1)
  • PROSITE:PS00022 (1)
  • PROSITE:PS01186 (1)
  • PROSITE:PS01187 (1)
  • PROSITE:PS50026 (1)
  • PROSITE:PS50088 (1)
  • PROSITE:PS50258 (1)
  • PROSITE:PS50297 (1)
  • Pfam:PF00008 (1)
  • Pfam:PF00066 (1)
  • Pfam:PF06816 (1)
  • Pfam:PF07645 (1)
  • Pfam:PF07684 (1)
  • Pfam:PF11936 (1)
  • Pfam:PF12661 (1)
  • Pfam:PF12796 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA notch1b-001 (1) 7824
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    SignaFish
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM notch1b No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    notch1bContained in: [BAC] DKEY-157G20 (order this), RP71-31M18 (1) (order this)
    notch1bEncodes: [EST] eu523 (1), fc55e11
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_131302 (1) 7797bp
    Genomic GenBank:BX119981 (1) 158974bp
    Select Tool
    Polypeptide UniProtKB:A0A0R4IMV9 (1) 2482aa
    Sequence Clusters UniGene:75825 (1)
    Sequence Information (all 25)
    OTHER notch1b GENE PAGES
  • Gene:794892 (1)
  • VEGA:OTTDARG00000019016 (1)
  • Ensembl(GRCz10):ENSDARG00000052094 (1)
  • ORTHOLOGY for notch1b (Chr: 5)
    CITATIONS (153)