ZFIN ID: ZDB-GENE-990415-181
Gene Name: nodal-related 2
Gene Symbol: ndr2
Sequence Ontology ID : SO:0000704

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Previous Names: Ndr-2, cyc-1 (1), cyc (1), cyclops (1), Znr-1, znr1

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(Including Attributions)
Location: Chr: 12 Mapping Details/Browsers
GENE EXPRESSION
All Expression Data: 49 figures from 39 publications
Wild-type Stages, Structures: Blastula:Sphere (4.0h-4.33h) to Pharyngula:Prim-5 (24.0h-30.0h)
  anatomical structure, axial chorda mesoderm, axial hypoblast, axial mesoderm (all 28) expand
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
b16 Deficiency Unknown Unknown G_RAYS
  • Zebrafish International Resource Center (ZIRC) (order this)
  • b426 Unknown Unknown Unknown ENU
    hi2718aTg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • m101 Unknown Unknown Unknown ENU
    m122 Unknown Unknown Unknown ENU
    m294 Unknown Unknown Unknown ENU
    ndr2_unspecified Unspecified Unknown Unknown
    sg1 Point Mutation Unknown Unknown ENU
    st5 Deficiency Unknown Unknown ENU
    te262c Unknown Unknown Unknown ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • tf219 Point Mutation Unknown Unknown ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • tu43x Unknown Unknown Unknown
  • European Zebrafish Resource Center (EZRC) (order this)
  • Targeting reagents: MO1-ndr2 (1), TALEN1-ndr2 (1), TALEN2-ndr2 (1)
    PHENOTYPE
    Data: 22 figures from 14 publications
    Observed in: anterior/posterior axon guidance, brain medial region, brain ventral region, brain (all 30) expand
    DISEASE ASSOCIATED WITH ndr2 HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    situs inversus Heterotaxy, visceral, 5 270100
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process dorsal/ventral pattern formation (more)
    Cellular Component extracellular region (more)
    Molecular Function growth factor activity (more)
    GO Terms (all 33)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR001111 (1)
  • InterPro:IPR001839 (1)
  • InterPro:IPR015615 (1)
  • InterPro:IPR017948 (1)
  • InterPro:IPR029034 (1)
  • PROSITE:PS00250 (1)
  • PROSITE:PS51362 (1)
  • Pfam:PF00019 (1)
  • Pfam:PF00688 (1)
  • TRANSCRIPTS No data available
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM ndr2 No data available
    MARKER RELATIONSHIPSNo data available
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_139133 (1)
    Polypeptide UniProtKB:A0A0B5JK91 (1) 501aa
    Sequence Clusters UniGene:18289 (1)
    Sequence Information (all 12)
    OTHER ndr2 GENE PAGES
  • Alliance (1)
  • Gene:30292 (1)
  • Ensembl(GRCz10):ENSDARG00000101279 (1)
  • ORTHOLOGY for ndr2 (Chr: 12)
    CITATIONS (264)