ZFIN ID: ZDB-GENE-990415-18
Gene Name: hemoglobin, beta adult 1
Gene Symbol: hbba1    Nomenclature History

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Previous Names: ba1, ba2, hbb (1), si:bY187G17.2 (1), si:dZ118J2.3 (1), zgc:123164, zgc:136512

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 3 Mapping Details/Browsers
Description: Predicted to have oxygen carrier activity. Involved in response to hypoxia. Predicted to localize to hemoglobin complex. Is expressed in brain; eye; intermediate cell mass of mesoderm; and vasculature. Human ortholog(s) of this gene implicated in sickle cell anemia. Orthologous to human HBE1 (hemoglobin subunit epsilon 1).
Genome Resources: Alliance (1), 
GENE EXPRESSION
All Expression Data: 10 figures from 8 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:63973]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Adult (90d-730d, breeding adult)
 
High Throughput Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS No data available
PHENOTYPE No data available
DISEASE ASSOCIATED WITH hbba1 HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH hbba1 VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process response to hypoxia (more)
Cellular Component hemoglobin complex (more)
Molecular Function oxygen carrier activity (more)
GO Terms (all 13)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA hbba1-201 (1)    Ensembl 667
ottdart00000002412 (1) 617
ncRNA ba1-002 (1)    Ensembl 713
ba1-003 (1)    Ensembl 543
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM hbba1 No data available
MARKER RELATIONSHIPS
hbba1 Contained in: [BAC] CH211-5K11 (1), XX-BY187G17
[PAC] BUSM1-118J2
hbba1 Encodes: [cDNA] MGC:63973 (1), MGC:123164, MGC:136512 (1), MGC:152838 (1), MGC:193846 (1), MGC:193857 (1)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:NM_131020 (1) 645 nt
Genomic GenBank:AL929176 100902 nt
Select Tool
Polypeptide UniProtKB:Q1RM32 (1) 148 aa
Sequence Information (all 19)
ORTHOLOGY for hbba1 ( Chr: 3 )
CITATIONS (47)