Gene

ntn1a

ID
ZDB-GENE-990415-169
Name
netrin 1a
Symbol
ntn1a Nomenclature History
Previous Names
  • net1a (1)
  • ntn2
  • net2
  • zgc:136732
Type
protein_coding_gene
Location
Chr: 6 Mapping Details/Browsers
Description
Involved in several processes, including circulatory system development; closure of optic fissure; and generation of neurons. Predicted to localize to basement membrane. Is expressed in several structures, including brain; head; optic cup; optic vesicle; and somite. Human ortholog(s) of this gene implicated in congenital mirror movement disorder. Orthologous to human NTN1 (netrin 1).
Genome Resources
Note
None
Expression
All Expression Data
31 figures from 22 publications
Cross-Species Comparison
High Throughput Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
17 figures from 10 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With ntn1a Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Mirror movements 4 618264
Associated With ntn1a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001134 Netrin domain
Domain IPR002049 Laminin EGF domain
Domain IPR008211 Laminin, N-terminal
Domain IPR018933 Netrin module, non-TIMP type
Homologous_superfamily IPR008979 Galactose-binding-like domain superfamily
Homologous_superfamily IPR008993 Tissue inhibitor of metalloproteinases-like, OB-fold
Homologous_superfamily IPR038684 Laminin, N-terminal domain superfamily
Domain Details Per Protein
Protein Length Galactose-binding-like domain superfamily Laminin EGF domain Laminin, N-terminal Laminin, N-terminal domain superfamily Netrin domain Netrin module, non-TIMP type Tissue inhibitor of metalloproteinases-like, OB-fold
UniProtKB:O42140 603
UniProtKB:A0A0R4IN40 446
UniProtKB:O13128 244
UniProtKB:Q29RD2 446
UniProtKB:A0A0B5JPZ7 603
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations