Gene

max

ID
ZDB-GENE-990415-152
Name
myc associated factor X
Symbol
max Nomenclature History
Previous Names
  • fa92b04
  • fb52a04
  • fb95h11
  • wu:fa92b04 (1)
  • wu:fb52a04 (1)
  • wu:fb95h11 (1)
  • zmax (1)
Type
protein_coding_gene
Location
Chr: 20 Mapping Details/Browsers
Description
Contributes to transcription regulatory region DNA binding activity. Involved in determination of ventral identity and hemopoiesis. Localizes to SMAD protein complex. Human ortholog(s) of this gene implicated in lung small cell carcinoma and pheochromocytoma. Is expressed in central nervous system. Orthologous to human MAX (MYC associated factor X).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
7 figures from 7 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
3 figures from 2 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With max Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
pheochromocytoma Alliance {Pheochromocytoma, susceptibility to} 171300
Associated With max Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR011598 Myc-type, basic helix-loop-helix (bHLH) domain
Family IPR037933 Protein max
Homologous_superfamily IPR036638 Helix-loop-helix DNA-binding domain superfamily
Domain Details Per Protein
Protein Length Helix-loop-helix DNA-binding domain superfamily Myc-type, basic helix-loop-helix (bHLH) domain Protein max
UniProtKB:Q6NY29 160
UniProtKB:P52161 165
UniProtKB:Q803J7 156
UniProtKB:Q5SPG2 151
UniProtKB:Q5SPG4 129
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations