Gene

psmb9a

ID

ZDB-GENE-990415-140

Name

proteasome 20S subunit beta 9a

Symbol

psmb9a Nomenclature History

Previous Names

lmp2
psmb9
beta1ia (1)
wu:fa66f04
wu:fj22d05
zgc:91842

Type

protein_coding_gene

Location

Chr: 19 Mapping Details/Browsers

Description

Predicted to have endopeptidase activity. Predicted to be involved in proteasomal ubiquitin-independent protein catabolic process and proteasome-mediated ubiquitin-dependent protein catabolic process. Predicted to localize to cytoplasm; nucleus; and proteasome core complex. Human ortholog(s) of this gene implicated in ankylosing spondylitis; autoimmune hypersensitivity disease (multiple); lymphoma; psoriasis; and renal cell carcinoma. Orthologous to human PSMB9 (proteasome 20S subunit beta 9).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

7 figures from 4 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

MGC:91842 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With psmb9a Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
		Proteasome-associated autoinflammatory syndrome 6	620796

Associated With psmb9a Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR016050	Proteasome beta-type subunit, conserved site
Family	IPR000243	Peptidase T1A, proteasome beta-subunit
Family	IPR001353	Proteasome, subunit alpha/beta
Family	IPR023333	Proteasome B-type subunit
Homologous_superfamily	IPR029055	Nucleophile aminohydrolases, N-terminal