Gene

isl2b

ID
ZDB-GENE-990415-133
Name
ISL LIM homeobox 2b
Symbol
isl2b Nomenclature History
Previous Names
  • isl3
  • zfIsl-3
  • zgc:109840
Type
protein_coding_gene
Location
Chr: 7 Mapping Details/Browsers
Description
Predicted to have DNA-binding transcription factor activity, RNA polymerase II-specific. Involved in exocrine pancreas development and secondary heart field specification. Predicted to localize to nucleus. Is expressed in several structures, including alar plate midbrain region; anterior lateral plate mesoderm; nervous system; pancreas; and trigeminal placode. Orthologous to human ISL2 (ISL LIM homeobox 2).
Genome Resources
Note
None
Expression
All Expression Data
16 figures from 7 publications
Cross-Species Comparison
High Throughput Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
2 figures from Witzel et al., 2017
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With isl2b Human Ortholog
No data available
Associated With isl2b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR017970 Homeobox, conserved site
Domain IPR001356 Homeobox domain
Domain IPR001781 Zinc finger, LIM-type
Homologous_superfamily IPR009057 Homeobox-like domain superfamily
Domain Details Per Protein
Protein Length Homeobox, conserved site Homeobox domain Homeobox-like domain superfamily Zinc finger, LIM-type
UniProtKB:P53407 358
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations