Gene
hesx1
- ID
- ZDB-GENE-990415-130
- Name
- HESX homeobox 1
- Symbol
- hesx1 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 11 Mapping Details/Browsers
- Description
- Predicted to have DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in forebrain development. Predicted to localize to nucleus. Is expressed in anterior presumptive neural plate; neural keel; neural plate; and telencephalon. Human ortholog(s) of this gene implicated in septooptic dysplasia. Orthologous to human HESX1 (HESX homeobox 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 27 figures from 19 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- eu608 (8 images)
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Young et al., 2019
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
Protein | Length | Homeobox, conserved site | Homeobox expressed in ES cells 1 |
---|---|---|---|
UniProtKB:P79738
|
161 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available