ZFIN ID: ZDB-GENE-990415-118
Gene Name: homeobox D12a
Gene Symbol: hoxd12a    Nomenclature History

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Previous Names: hoxd-12, hoxd12

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 9 Mapping Details/Browsers
Description: Predicted to have sequence-specific DNA binding activity. Predicted to be involved in multicellular organism development and regulation of transcription, DNA-templated. Predicted to localize to nucleus. Is expressed in several structures, including mesenchyme; pectoral fin; pectoral fin bud; pectoral fin field; and tail bud. Human ortholog(s) of this gene implicated in clubfoot. Orthologous to human HOXD12 (homeobox D12).
Genome Resources: Alliance (1),  Gene:100006598 (1),  Ensembl(GRCz11):ENSDARG00000059263 (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
ihb186 Insertion Unknown Unknown CRISPR
ihb187 Indel Unknown Unknown CRISPR
sa21419 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    CRISPR1-hoxd12a 1
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH hoxd12a HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH hoxd12a VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process multicellular organism development (more)
    Cellular Component nucleus (more)
    Molecular Function DNA binding (more)
    GO Terms (all 5)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA hoxd12a-202 (1)    Ensembl 1396
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    CONSTRUCTS WITH SEQUENCES FROM hoxd12a No data available
    MARKER RELATIONSHIPS
    hoxd12a Contained in: [BAC] RP71-78H1 (1)
    hoxd12a Encodes: [EST] IMAGE:6901952 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001126486 (1) 1309 nt
    Genomic GenBank:BX322661 (1) 146527 nt
    Select Tool
    Polypeptide UniProtKB:B0S5Y9 (1) 277 aa
    Sequence Information (all 17)
    ORTHOLOGY for hoxd12a ( Chr: 9 )
    CITATIONS (42)