Gene
hoxb8a
- ID
- ZDB-GENE-990415-108
- Name
- homeobox B8a
- Symbol
- hoxb8a Nomenclature History
- Previous Names
-
- gp-8
- hoxb8
- fj67g02
- wu:fj67g02 (1)
- Type
- protein_coding_gene
- Location
- Chr: 3 Mapping Details/Browsers
- Description
- Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Acts upstream of or within cell population proliferation and posterior lateral line neuromast primordium migration. Predicted to be active in nucleus. Is expressed in several structures, including nervous system; neural tube; pancreatic system; paraxial mesoderm; and pronephros. Orthologous to human HOXB8 (homeobox B8).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 12 figures from 6 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:64159 (8 images)
Wild Type Expression Summary
- All Phenotype Data
- 2 figures from Breau et al., 2013
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Type | InterPro ID | Name |
---|---|---|
Conserved_site | IPR000047 | Helix-turn-helix motif |
Conserved_site | IPR001827 | Homeobox protein, antennapedia type, conserved site |
Conserved_site | IPR017970 | Homeobox, conserved site |
Domain | IPR001356 | Homeobox domain |
Domain | IPR020479 | Homeobox domain, metazoa |
Homologous_superfamily | IPR009057 | Homeobox-like domain superfamily |
Domain Details Per Protein
Protein | Length | Helix-turn-helix motif | Homeobox, conserved site | Homeobox domain | Homeobox domain, metazoa | Homeobox-like domain superfamily | Homeobox protein, antennapedia type, conserved site |
---|---|---|---|---|---|---|---|
UniProtKB:Q8AWZ0
|
245 |
Type | Name | Length (nt) | Analysis |
---|---|---|---|
mRNA |
hoxb8a-201
(1)
|
1817 nt | |
mRNA | ottdart00000001809 (1) | 1752 nt |
Interactions and Pathways
No data available
Plasmids