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General Information
ZIRC
ZFIN ID: ZDB-GENE-980605-23
Gene Name: protein tyrosine phosphatase non-receptor type 1
Gene Symbol: ptpn1
Sequence Ontology ID : SO:0001217

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Previous Names: PTP-1B (1), ptp1b, fk54h03, wu:fk54h03

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(Including Attributions)
Location: Chr: 8 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have protein tyrosine phosphatase activity. Predicted to be involved in protein dephosphorylation. Human ortholog(s) of this gene implicated in type 2 diabetes mellitus. Is expressed in  ...
GENE EXPRESSION
All Expression Data: 3 figures from 3 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:66113]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Adult (90d-730d, breeding adult)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Targeting reagents:
PHENOTYPE No data available
DISEASE ASSOCIATED WITH ptpn1 HUMAN ORTHOLOG
Disease Ontology Term OMIM Term OMIM Phenotype ID
type 2 diabetes mellitus {Insulin resistance, susceptibility to} 125853
DISEASE ASSOCIATED WITH ptpn1 VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process dephosphorylation (more)
Molecular Function hydrolase activity (more)
GO Terms (all 6)
 Withdrawn Transcriptsextinct
GENE PRODUCT DESCRIPTION
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM ptpn1 No data available
MARKER RELATIONSHIPS
ptpn1 Contained in: [BAC] DKEYP-53E12 (1)
ptpn1 Encodes: [EST] fk54h03 (1)
[cDNA] MGC:66113 (1) (order this), MGC:191909 (1) (order this)
SEQUENCE INFORMATION
Type Accession # Length (bp/aa) Analysis
RNA RefSeq:NM_130924 (1) 3489 bp
Genomic GenBank:BX322655 184723 bp
Select Tool
Polypeptide UniProtKB:Q7ZWI6 (1) 461 aa
Sequence Clusters UniGene:8290 (1)
Sequence Information (all 38)
OTHER ptpn1 GENE PAGES
  • Alliance (1)
  • Gene:30081 (1)
  • Ensembl(GRCz11):ENSDARG00000007923 (2)
  • ORTHOLOGY for ptpn1 ( Chr: 8 )
    CITATIONS (26)