ZFIN ID: ZDB-GENE-980526-89
Gene Name: smoothened, frizzled class receptor
Gene Symbol: smo
Sequence Ontology ID : SO:0000704

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Previous Names: CHUNP6862, slow muscle omitted, smoh, smoothened (1), smu, wu:fb70b01, wu:fc39h03

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(Including Attributions)
Location: Chr: 4 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 7 figures from 6 publications
Wild-type Stages, Structures: Cleavage:2-cell (0.75h-1.0h) to Hatching:Long-pec (48.0h-60.0h)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
b577 Point Mutation Unknown Unknown ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • b641 Point Mutation Unknown Unknown ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • hi229Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • hi1640Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • hi2329bTg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • jj392 Unknown Unknown Unknown ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la010329Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • m841 Unknown Unknown Unknown ENU
    nv122 Point Mutation Unknown Premature Stop
    s294 Point Mutation Unknown Unknown
    sa38433 Point Mutation Unknown Premature Stop ENU
    smo_unspecified Unspecified Unknown Unknown
    zf642 Unknown Unknown Unknown ENU
    Targeting reagents:
    PHENOTYPE
    Data: 89 figures from 52 publications
    Observed in:
    DISEASE ASSOCIATED WITH smo HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    Basal cell carcinoma, somatic
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process embryonic camera-type eye development (more)
    Cellular Component cilium (more)
    Molecular Function oxysterol binding (more)
    GO Terms (all 75)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000539 (1)
  • InterPro:IPR015526 (1)
  • InterPro:IPR017981 (1)
  • InterPro:IPR020067 (1)
  • InterPro:IPR026544 (1)
  • InterPro:IPR035683 (1)
  • InterPro:IPR036790 (1)
  • PROSITE:PS50038 (1)
  • PROSITE:PS50261 (1)
  • Pfam:PF01392 (1)
  • Pfam:PF01534 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA smo-001 (1) 6212
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    SignaFish
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM smo
    MARKER RELATIONSHIPS
    smoContained in: [BAC] DKEY-180P18 (1) (order this)
    smoEncodes: [BAC END] zk11h20.sp6
    [EST] fb70b01 (1), fc39h03 (1)
    [cDNA] zv1 (1), zv2 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_131027 (1) 2880bp
    Genomic GenBank:BX571796 (1) 130699bp
    Select Tool
    Polypeptide UniProtKB:Q5RH73 (1) 822aa
    Sequence Clusters UniGene:114683 (1)
    Sequence Information (all 19)
    OTHER smo GENE PAGES
  • Alliance (1)
  • Gene:30225 (1)
  • VEGA:OTTDARG00000007795 (1)
  • Ensembl(GRCz10):ENSDARG00000002952 (1)
  • ORTHOLOGY for smo (Chr: 4)
    CITATIONS (247)