ZFIN ID: ZDB-GENE-980526-549
Gene Name: activin A receptor type 2Ba
Gene Symbol: acvr2ba
Sequence Ontology ID : SO:0000704

{{control.fieldName}} Edit

ID: {{control.nomenID}}
{{control.fieldName}}:
Reason:
Comments:

Attributions

{{pub.zdbID}}
Previous Names: actr2b, actrIIb, acvr2b, wu:fj97d11

Add new Alias

Alias
Attribution

Attributions for Alias: {{control.newAlias}}

{{pub.zdbID}}

Delete Alias:

(Including Attributions)
Location: Chr: 24 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have several functions, including SMAD binding activity, activin binding activity, and growth factor binding activity; involved in cartilage development, hindbrain development, and  ...
GENE EXPRESSION
All Expression Data: 17 figures from 6 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:113962]
  6 figures (5 images) from Thisse et al., 2005 [eu356]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Adult (90d-730d, breeding adult)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la014617Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la014618Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Targeting reagents:
    PHENOTYPE
    Data: 2 figures from Albertson et al., 2005
    Observed in:
    DISEASE ASSOCIATED WITH acvr2ba HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    visceral heterotaxy Heterotaxy, visceral, 4, autosomal 613751
    DISEASE ASSOCIATED WITH acvr2ba VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process cartilage development (more)
    Cellular Component integral component of membrane (more)
    Molecular Function ATP binding (more)
    GO Terms (all 17)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000333 (1)
  • InterPro:IPR000472 (1)
  • InterPro:IPR000719 (1)
  • InterPro:IPR001245 (1)
  • InterPro:IPR008271 (1)
  • InterPro:IPR011009 (1)
  • PROSITE:PS00108 (1)
  • PROSITE:PS50011 (1)
  • Pfam:PF00069 (1)
  • Pfam:PF01064 (1)
  • Pfam:PF07714 (1)
  • EC:2.7.11.30 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA acvr2ba-203 (1) 674
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    SignaFish
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM acvr2ba No data available
    MARKER RELATIONSHIPS
    acvr2baContained in: [Fosmid] CH1073-202A14 (1) (order this)
    acvr2baEncodes: [EST] eu356 (1), fj97d11
    [cDNA] MGC:55235 (1) (order this), MGC:113962 (1) (order this), MGC:191394 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_131210 (1) 4403bp
    Genomic GenBank:CU467626 (1) 42495bp
    Select Tool
    Polypeptide UniProtKB:F1QLL7 (1) 509aa
    Sequence Clusters UniGene:75136 (1)
    Sequence Information (all 33)
    OTHER acvr2ba GENE PAGES
  • Alliance (1)
  • Gene:30457 (1)
  • VEGA:OTTDARG00000034808 (1)
  • Ensembl(GRCz11):ENSDARG00000044422 (2)
  • ORTHOLOGY for acvr2ba (Chr: 24)
    CITATIONS (47)