ZFIN ID: ZDB-GENE-980526-529
Gene Name: v-myb avian myeloblastosis viral oncogene homolog-like 2a
Gene Symbol: mybl2a    Nomenclature History

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Previous Names: myb, fd99g04, wu:fd99g04

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 23 Mapping Details/Browsers
Description: Predicted to have DNA binding activity and protein dimerization activity. Predicted to be involved in mitotic cell cycle and positive regulation of transcription, DNA-templated. Predicted to localize to the nucleus. Is expressed in dorsal aorta; hematopoietic stem cell; and intermediate cell mass of mesoderm. Orthologous to human MYBL2 (MYB proto-oncogene like 2).
Genome Resources: Alliance (1),  Gene:100005189 (1),  Ensembl(GRCz11):ENSDARG00000095241 (2)
GENE EXPRESSION
All Expression Data: 4 figures from 4 publications
Wild-type Stages, Structures: Segmentation:26+ somites (22.0h-24.0h) to Pharyngula:Prim-25 (36.0h-42.0h)
 
Curated Microarray Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa10000 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH mybl2a HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH mybl2a VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process mitotic cell cycle (more)
    Cellular Component nucleus (more)
    Molecular Function DNA binding (more)
    GO Terms (all 6)
    PROTEIN FAMILIES, DOMAINS AND SITES
    Type InterPro ID Name
    Domain IPR001005 SANT/Myb domain
    Domain IPR008906 HAT, C-terminal dimerisation domain
    Domain IPR017930 Myb domain
    Family IPR015495 Myb-like transcription factor
    Homologous_superfamily IPR009057 Homeobox-like domain superfamily
    Homologous_superfamily IPR012337 Ribonuclease H-like superfamily
    Homologous_superfamily IPR037220 Zinc finger BED domain
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA mybl2a-201 (1)    Ensembl 2810
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM mybl2a No data available
    MARKER RELATIONSHIPS
    mybl2a Contained in: [BAC] CH73-142C19 (1)
    mybl2a Encodes: [EST] fd99g04
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001309826 (1)
    Genomic GenBank:CU571072 (1) 93305 nt
    Select Tool
    Polypeptide UniProtKB:A0A2R8QH49 (1) 806 aa
    Sequence Information (all 10)
    ORTHOLOGY for mybl2a ( Chr: 23 )
    CITATIONS (23)