ZFIN Gene: wnt8a

ZFIN ID: ZDB-GENE-980526-332

ZFIN ID: ZDB-GENE-980526-332

Gene Name:	wingless-type MMTV integration site family, member 8a
Gene Symbol:	wnt8a
Previous Names:	wnt8, wnt8.1 (1), etID309727.14 (1), wnt8 ORF1 (1), wnt8 ORF2 (1), wu:fa20e02, wu:fe05d07
Location:	Chr: 14 Details
Nomenclature History

GENE EXPRESSION
All Expression Data:	36 figures from 34 publications
Wild-type Stages, Structures:	Zygote:1-cell (0.0h-0.75h) to Adult (90d-730d, breeding adult)
	blastoderm lower region , head , margin , mesoderm (all 15)
Curated Microarray Expression:	GEO (1)

MUTANTS AND TARGETED KNOCKDOWNS

Mutant lines:	4 genotypes
Alleles:	la011030Tg, la018995Tg, sa11601, w11, w8
Knockdown reagents:	MO1-wnt8a (1), MO2-wnt8a (1), MO3-wnt8a (1), MO4-wnt8a (1), MO5-wnt8a (1) (all 7)

PHENOTYPE

Data:	19 figures from 13 publications
Observed in:	axis , brain , embryonic heart tube left/right pattern formation , embryonic pattern specification (all 31)

GENE ONTOLOGY

Ontology	GO Term
Biological Process	anterior/posterior pattern specification (more)
Cellular Component	extracellular region (more)
Molecular Function	metal ion binding (more)

GO Terms (all 38)

PROTEIN FAMILIES, DOMAINS AND SITES
InterPro:IPR005817 (1) InterPro:IPR007087 (1) InterPro:IPR013301 (1) InterPro:IPR018161 (1)	PROSITE:PS00028 (1) PROSITE:PS00246 (1)	Pfam:PF00110 (1)

TRANSCRIPTS
Type	Name	Length (bp)	Analysis
mRNA	ottdart00000025912 (1)	1680	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT Vega
ncRNA	ottdart00000025917 (1)	906	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT Vega
mRNA	wnt8a-001 (1)	1763	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT Vega
ncRNA	wnt8a-002 (1)	3207	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT Vega
mRNA	wnt8a-003 (1)	554	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT Vega
	wnt8a-004 (1)	884	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT Vega

GENE PRODUCT DESCRIPTION

ANTIBODIES No data available

CONSTRUCTS WITH SEQUENCES FROM wnt8a

Tg(-1.3wnt8a:EGFP), Tg(-1.8wnt8a:EGFP), Tg(-2.8wnt8a:EGFP), Tg(hsp70l:wnt8a-GFP), Tg1(-2.8wnt8a:EGFP) (all 20) expand

SEGMENT (CLONE AND PROBE) RELATIONSHIPS

wnt8a Contained in:	[BAC] CH211-11C15 (1) (order this), CH211-232M8 (1) (order this)
wnt8a Encodes:	[EST] fa20e02, fe05d07 [cDNA] MGC:66187 (1) (order this), MGC:191351 (1) (order this)

SEQUENCE INFORMATION

Type	Accession #	Length (bp/aa)	Analysis
RNA	GenBank:U10869 (1)	3022 bp	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT Vega
Genomic	GenBank:BX927327 (1)	182779 bp	Select Tool MegaBLAST Ensembl
Polypeptide	UniProtKB:B8A6B9 (1)	387 aa	Select Tool ZFIN BLAST SIB BLAST Ensembl Protein Blast Vega Protein Blast

OTHER wnt8a GENE PAGES

VEGA:OTTDARG00000020652 (1)

VEGA:OTTDARG00000020653 (1)

ORTHOLOGY

CITATIONS (150)