ZFIN ID: ZDB-GENE-980526-332
Gene Name: wingless-type MMTV integration site family, member 8a
Gene Symbol: wnt8a
Previous Names: wnt8.1 (1), wnt8, etID309727.14 (1), wnt8 ORF1 (1), wnt8 ORF2 (1), wu:fa20e02, wu:fe05d07
Location: Chr: 14 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 47 figures from 42 publications
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Adult (90d-730d, breeding adult)
  adaxial cell, anatomical structure, blastoderm lower region, blastomere (all 23) expand
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la011030Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la018995Tg Transgenic Insertion Unknown Unknown DNA
    sa11601 Point Mutation Unknown Unknown ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • European Zebrafish Resource Center (EZRC) (order this)
  • Targeting reagents: MO1-wnt8a (1), MO2-wnt8a (1), MO3-wnt8a (1), MO4-wnt8a (1), MO5-wnt8a (1) (all 7) expand
    PHENOTYPE
    Data: 19 figures from 13 publications
    Observed in: axis, brain, embryonic heart tube left/right pattern formation, embryonic pattern specification (all 31) expand
    DISEASE ASSOCIATED WITH wnt8a HUMAN ORTHOLOGNo data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process anterior/posterior pattern specification (more)
    Cellular Component extracellular region (more)
    Molecular Function metal ion binding (more)
    GO Terms (all 36)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR005817 (1)
  • InterPro:IPR007087 (1)
  • InterPro:IPR013301 (1)
  • InterPro:IPR018161 (1)
  • PROSITE:PS00028 (1)
  • PROSITE:PS00246 (1)
  • Pfam:PF00110 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA ottdart00000025912 (1) 1680
    ncRNA ottdart00000025913 (1) 3207
    ottdart00000063240 (1) 906
    mRNA wnt8a-001 (1) 1208
    wnt8a-003 (1) 554
    wnt8a-004 (1) 884
     Withdrawn Transcriptsextinct
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    SignaFish
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM wnt8a
    Tg(-1.3wnt8a:EGFP), Tg(-1.8wnt8a:EGFP), Tg(-2.8wnt8a:EGFP), Tg(hsp70l:wnt8a-GFP), Tg(UAS:wnt8a-UTRnanos3) (all 21) expand
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    wnt8aContained in: [BAC] CH211-11C15 (1) (order this), CH211-232M8 (1) (order this)
    wnt8aEncodes: [EST] fa20e02, fe05d07
    [cDNA] MGC:66187 (1) (order this), MGC:191351 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA GenBank:U10869 (1) 3022bp
    Genomic GenBank:BX927327 (1) 182779bp
    Select Tool
    Polypeptide UniProtKB:B8A6B9 (1) 387aa
    Sequence Information (all 20)
    OTHER wnt8a GENE PAGES
  • VEGA:OTTDARG00000020652 (1)
  • VEGA:OTTDARG00000020653 (1)
  • VEGA:OTTDARG00000043343 (1)
  • ORTHOLOGY for wnt8a (Chr: 14)
    Species Symbol Chromosome Accession # Evidence
    Human WNT8A 5
  • Gene:7478
  • OMIM:606360
  • HGNC:12788
  • Amino acid sequence comparison (2)
    Mouse Wnt8a 18
  • MGI:107924
  • Gene:20890
  • Amino acid sequence comparison (4)
    Download Curated Orthology
    CITATIONS (179)