Research
General Information
ZIRC
ZFIN ID: ZDB-GENE-980526-332
Gene Name: wingless-type MMTV integration site family, member 8a
Gene Symbol: wnt8a
Previous Names: wnt8, wnt8.1 (1), etID309727.14 (1), wnt8 ORF1 (1), wnt8 ORF2 (1), wu:fa20e02, wu:fe05d07
Location: Chr: 14   Details
Nomenclature History
GENE EXPRESSION
All Expression Data: 39 figures from 34 publications
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Adult (90d-730d, breeding adult)
  adaxial cell, axial mesoderm, blastoderm lower region, head (all 18) expand
Curated Microarray Expression: GEO (1)
MUTANTS AND TARGETED KNOCKDOWNS
Mutant lines: 4 genotypes
Alleles: la011030Tg, la018995Tg, sa11601, w11, w8
Knockdown reagents: MO1-wnt8a (1), MO2-wnt8a (1), MO3-wnt8a (1), MO4-wnt8a (1), MO5-wnt8a (1) (all 7) expand
PHENOTYPE
Data: 19 figures from 13 publications
Observed in: axis, brain, embryonic heart tube left/right pattern formation, embryonic pattern specification (all 31) expand
GENE ONTOLOGY
Ontology GO Term
Biological Process anterior/posterior pattern specification (more)
Cellular Component extracellular region (more)
Molecular Function metal ion binding (more)
GO Terms (all 38)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR005817 (1)
  • InterPro:IPR007087 (1)
  • InterPro:IPR013301 (1)
  • InterPro:IPR018161 (1)
  • PROSITE:PS00028 (1)
  • PROSITE:PS00246 (1)
  • Pfam:PF00110 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA ottdart00000025912 (1) 1680
    ncRNA ottdart00000025917 (1) 906
    mRNA wnt8a-001 (1) 1763
    ncRNA wnt8a-002 (1) 3207
    mRNA wnt8a-003 (1) 554
    wnt8a-004 (1) 884
    GENE PRODUCT DESCRIPTION
    ANTIBODIES No data available
    CONSTRUCTS WITH SEQUENCES FROM wnt8a
    Tg(-1.3wnt8a:EGFP), Tg(-1.8wnt8a:EGFP), Tg(-2.8wnt8a:EGFP), Tg(hsp70l:wnt8a-GFP), Tg1(-2.8wnt8a:EGFP) (all 20) expand
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    wnt8a Contained in: [BAC] CH211-11C15 (1) (order this), CH211-232M8 (1) (order this)
    wnt8a Encodes: [EST] fa20e02, fe05d07
    [cDNA] MGC:66187 (1) (order this), MGC:191351 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA GenBank:U10869 (1) 3022 bp
    Genomic GenBank:BX927327 (1) 182779 bp
    Select Tool
    Polypeptide UniProtKB:B8A6B9 (1) 387 aa
    Sequence Information (all 20)
    OTHER wnt8a GENE PAGES
  • VEGA:OTTDARG00000020652 (1)
  • VEGA:OTTDARG00000020653 (1)
  • ORTHOLOGY
      Evidence
    Species Symbol Chr (Position) Accession # AA
    Zebrafish wnt8a 14  
    Human WNT8A 5 (5q31)
  • OMIM:606360
  • Gene:7478
  • Mouse Wnt8a 18 ( 18.69 cM)
  • MGI:107924
  • Gene:20890
  • Orthology Details
    CITATIONS (150)