ZFIN ID: ZDB-GENE-980526-332
Your Input Welcome
We welcome your input and comments. Please use this form to recommend updates to the information in ZFIN. We appreciate as much detail as possible and references as appropriate. We will review your comments promptly.
Please check the highlighted fields and try again.
Thank you for submitting comments. Your input has been emailed to ZFIN curators who may contact you if additional information is required.
Oops. Something went wrong. Please try again later.
Gene Name: wingless-type MMTV integration site family, member 8a
Gene Symbol: wnt8a
Sequence Ontology ID : SO:0000704

{{control.fieldName}} Edit

ID: {{control.nomenID}}
{{control.fieldName}}:
Reason:
Comments:

Attributions

{{pub.zdbID}}
Previous Names: wnt8.1 (1), wnt8, etID309727.14 (1), wnt8 ORF1 (1), wnt8 ORF2 (1), wu:fa20e02, wu:fe05d07

Add new Alias

Alias
Attribution

Attributions for Alias: {{control.newAlias}}

{{pub.zdbID}}

Delete Alias:

(Including Attributions)
Location: Chr: 14 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 52 figures from 46 publications
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Adult (90d-730d, breeding adult)
  adaxial cell, anatomical structure, blastoderm lower region, blastomere (all 32) expand
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la011030Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
    • la018995Tg Transgenic Insertion Unknown Unknown DNA
    nub14 Small Deletion Unknown Unknown TALEN
    nub15 Small Deletion Unknown Unknown TALEN
    nub16 Small Deletion Unknown Unknown TALEN
    nub17 Indel Unknown Unknown TALEN
    nub18 Small Deletion Unknown Unknown TALEN
    nub19 Complex Unknown Unknown TALEN
    nub20 Complex Unknown Unknown TALEN
    nub21 Complex Unknown Unknown TALEN
    nub22 Small Deletion Unknown Unknown TALEN
    sa1188 Point Mutation Unknown Splice Site ENU
    sa11601 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
    • sa31997 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
    • sa35723 Point Mutation Unknown Splice Site ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • European Zebrafish Resource Center (EZRC) (order this)
    • sa42419 Point Mutation Unknown Premature Stop ENU
    Targeting reagents: CRISPR1-wnt8a (1), CRISPR2-wnt8a (1), CRISPR3-wnt8a (1), CRISPR4-wnt8a (1), MO1-wnt8a (1) (all 14) expand
    PHENOTYPE
    Data: 31 figures from 17 publications
    Observed in: apoptotic process, axial mesoderm, axis, brain (all 55) expand
    DISEASE ASSOCIATED WITH wnt8a HUMAN ORTHOLOGNo data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process anterior/posterior pattern specification (more)
    Cellular Component extracellular matrix (more)
    Molecular Function nucleic acid binding (more)
    GO Terms (all 40)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR005817 (1)
  • InterPro:IPR013087 (1)
  • InterPro:IPR013301 (1)
  • InterPro:IPR018161 (1)
  • InterPro:IPR034312 (1)
    		•
  • PROSITE:PS00028 (1)
  • PROSITE:PS00246 (1)
    		•
  • Pfam:PF00110 (1)
    		•
    TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA ottdart00000025912 (1) 1680
    Select Tool
    ncRNA ottdart00000025913 (1) 3207
    Select Tool
    mRNA wnt8a-001 (1) 1208
    Select Tool
    ncRNA wnt8a-002 (1) 906
    Select Tool
    mRNA wnt8a-003 (1) 554
    Select Tool
    wnt8a-004 (1) 884
    Select Tool
     Withdrawn Transcriptsextinct
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    SignaFish
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM wnt8a
    Tg(-1.3wnt8a:EGFP), Tg(-1.8wnt8a:EGFP), Tg(-2.8wnt8a:EGFP), Tg(hsp70l:wnt8a-GFP), tg(uas:wnt8a-utrnanos3) (all 21) expand
    MARKER RELATIONSHIPS
    wnt8aContained in: [BAC] CH211-11C15 (1) (order this), CH211-232M8 (1) (order this)
    wnt8aEncodes: [EST] fa20e02, fe05d07
    [cDNA] MGC:66187 (1) (order this), MGC:191351 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA GenBank:U10869 (1) 3022bp
    Select Tool
    Genomic GenBank:BX927327 (1) 182779bp
    Select Tool
    Polypeptide UniProtKB:B8A6B9 (1) 387aa
    Select Tool
    Sequence Information (all 20)
    OTHER wnt8a GENE PAGES
  • Alliance (1)
  • VEGA:OTTDARG00000020652 (1)
  • VEGA:OTTDARG00000020653 (1)
  • VEGA:OTTDARG00000043343 (1)
  • Ensembl(GRCz10):ENSDARG00000052910 (1)
  • Ensembl(GRCz10):ENSDARG00000078507 (1)
    • ORTHOLOGY for wnt8a (Chr: 14)
    CITATIONS (218)