Gene
wnt8a
- ID
- ZDB-GENE-980526-332
- Name
- wingless-type MMTV integration site family, member 8a
- Symbol
- wnt8a Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 14 Mapping Details/Browsers
- Description
- Predicted to enable cytokine activity and frizzled binding activity. Involved in embryonic axis specification; neural crest cell fate specification; and positive regulation of canonical Wnt signaling pathway. Acts upstream of or within with a positive effect on regulation of cell population proliferation. Acts upstream of or within several processes, including animal organ development; gastrulation; and regionalization. Located in apoptotic body and cell surface. Is expressed in several structures, including germ ring; mesoderm; oocyte; presumptive paraxial mesoderm; and unfertilized egg. Orthologous to human WNT8A (Wnt family member 8A).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 58 figures from 52 publications
- Cross-Species Comparison
- High Throughput Data
-
- GEO (1) Expression Atlas (1) UCSC scRNA-seq (1) UCSC scRNA-seq (1)
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 35 figures from 19 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Protein Wnt-8A/8C | Wnt | Wnt-8 protein | Wnt, C-terminal domain | Wnt protein, conserved site | Zinc finger C2H2-type |
|---|---|---|---|---|---|---|---|
|
UniProtKB:B8A6C0
|
161 | ||||||
|
UniProtKB:B2GP18
|
359 | ||||||
|
UniProtKB:B8A4J5
|
353 | ||||||
|
UniProtKB:Q90YJ8
|
354 | ||||||
|
UniProtKB:Q90YL8
|
354 | ||||||
|
UniProtKB:B8A6B9
|
387 | ||||||
|
UniProtKB:B8A6C1
|
263 | ||||||
|
UniProtKB:P51028
|
359 |
Interactions and Pathways
Plasmids
No data available
- Comparative Orthology
- Alliance