Gene

egr1

ID
ZDB-GENE-980526-320
Name
early growth response 1
Symbol
egr1 Nomenclature History
Previous Names
  • etID309970.14 (1)
  • krox-24
  • krox24
  • wu:fj64b05
  • wu:fq25f01
Type
protein_coding_gene
Location
Chr: 14 Mapping Details/Browsers
Description
Predicted to have several functions, including DNA binding activity; DNA-binding transcription factor activity, RNA polymerase II-specific; and promoter-specific chromatin binding activity. Involved in embryonic retina morphogenesis in camera-type eye and embryonic viscerocranium morphogenesis. Predicted to localize to cytoplasm and nucleus. Human ortholog(s) of this gene implicated in asthma and myeloid neoplasm. Is expressed in head; heart; hindbrain neural keel; mesoderm; and nervous system. Orthologous to human EGR1 (early growth response 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
29 figures from 13 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
12 figures from 4 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With egr1 Human Ortholog
No data available
Associated With egr1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR013087 Zinc finger C2H2-type
Domain IPR021849 Early growth response, N-terminal
Homologous_superfamily IPR036236 Zinc finger C2H2 superfamily
Repeat IPR021839 Early growth response protein 1, C-terminal
Domain Details Per Protein
Protein Length Early growth response, N-terminal Early growth response protein 1, C-terminal Zinc finger C2H2 superfamily Zinc finger C2H2-type
UniProtKB:B3DKJ7 511
UniProtKB:P26632 511
UniProtKB:C5IG42 247
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations