Gene

otx2a

ID
ZDB-GENE-980526-27
Name
orthodenticle homeobox 2a
Symbol
otx2a Nomenclature History
Previous Names
  • otx1a
  • otx1l
  • otx3
Type
protein_coding_gene
Location
Chr: 1 Mapping Details/Browsers
Description
Predicted to have DNA binding activity and DNA-binding transcription factor activity, RNA polymerase II-specific. Involved in brain development and retinal pigment epithelium development. Predicted to localize to nucleus. Is expressed in several structures, including anterior neural keel; axis; brain; immature eye; and neural plate. Orthologous to human OTX1 (orthodenticle homeobox 1).
Genome Resources
Note
None
Expression
All Expression Data
17 figures from 9 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With otx2a Human Ortholog
No data available
Associated With otx2a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR017970 Homeobox, conserved site
Domain IPR001356 Homeobox domain
Domain IPR013851 Transcription factor Otx, C-terminal
Family IPR003025 Transcription factor Otx
Homologous_superfamily IPR009057 Homeobox-like domain superfamily
Domain Details Per Protein
Protein Length Homeobox, conserved site Homeobox domain Homeobox-like domain superfamily Transcription factor Otx Transcription factor Otx, C-terminal
UniProtKB:Q90267 338
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Gene Tree
Ensembl
Citations