ZFIN ID: ZDB-GENE-980526-27
Gene Name: orthodenticle homeobox 2a
Gene Symbol: otx2a
Sequence Ontology ID : SO:0000704

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Previous Names: otx1a, otx1l, otx3

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(Including Attributions)
Location: Chr: 1 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 16 figures from 8 publications
Directly Submitted Expression Data: 6 figures (20 images) from Thisse et al., 2005 [eu812]
Wild-type Stages, Structures: Gastrula:50%-epiboly (5.25h-5.66h) to Hatching:Long-pec (48.0h-60.0h)
  axis, central nervous system, diencephalon, epiphysis (all 28) expand
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa12472 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • European Zebrafish Resource Center (EZRC) (order this)
  • sa19590 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • European Zebrafish Resource Center (EZRC) (order this)
  • zko985a Small Deletion Unknown Unknown CRISPR
    zko985b Small Deletion Unknown Unknown CRISPR
    Targeting reagents: CRISPR1-otx2a (1), MO1-otx2a (1)
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH otx2a HUMAN ORTHOLOGNo data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process cerebellum development (more)
    Cellular Component nucleus (more)
    Molecular Function DNA binding (more)
    GO Terms (all 11)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR001356 (1)
  • InterPro:IPR003025 (1)
  • InterPro:IPR009057 (1)
  • InterPro:IPR013851 (1)
  • InterPro:IPR017970 (1)
  • PROSITE:PS00027 (1)
  • PROSITE:PS50071 (1)
  • Pfam:PF00046 (1)
  • Pfam:PF03529 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA otx1a-001 (1) 1629
    ncRNA otx1a-002 (1) 583
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM otx2a No data available
    MARKER RELATIONSHIPS
    otx2aContained in: [BAC] DKEYP-123H10 (1)
    otx2aEncodes: [EST] eu812 (1)
    [cDNA] MGC:100760 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_131215 (1) 1660bp
    Genomic GenBank:BX855617 (1) 160094bp
    Select Tool
    Polypeptide UniProtKB:Q90267 (1) 338aa
    Sequence Clusters UniGene:75758 (1)
    Sequence Information (all 14)
    OTHER otx2a GENE PAGES
  • Alliance (1)
  • Gene:30462 (1)
  • VEGA:OTTDARG00000019690 (1)
  • Ensembl(GRCz10):ENSDARG00000030703 (1)
  • ORTHOLOGY for otx2a (Chr: 1)
    CITATIONS (44)