ZFIN ID: ZDB-GENE-980526-227
Gene Name: activin A receptor type 2Aa
Gene Symbol: acvr2aa
Sequence Ontology ID : SO:0000704

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Previous Names: actr2a (1), acvr2, acvr2a, etID22865.9 (1), wu:fa02e10

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(Including Attributions)
Location: Chr: 9 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have several functions, including SMAD binding activity, activin binding activity, and growth factor binding activity; involved in cartilage development, hindbrain development, and  ...
GENE EXPRESSION
All Expression Data: 7 figures from 3 publications
Wild-type Stages, Structures: Cleavage:2-cell (0.75h-1.0h) to Adult (90d-730d, breeding adult)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa34653 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa34654 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Targeting reagents:
    PHENOTYPE
    Data: 3 figures from Albertson et al., 2005
    Observed in:
    DISEASE ASSOCIATED WITH acvr2aa HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH acvr2aa VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process cartilage development (more)
    Cellular Component integral component of membrane (more)
    Molecular Function ATP binding (more)
    GO Terms (all 20)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000333 (1)
  • InterPro:IPR000472 (1)
  • InterPro:IPR000719 (1)
  • InterPro:IPR008271 (1)
  • InterPro:IPR011009 (1)
  • InterPro:IPR017194 (1)
  • PROSITE:PS00108 (1)
  • PROSITE:PS50011 (1)
  • Pfam:PF00069 (1)
  • Pfam:PF01064 (1)
  • EC:2.7.11.30 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    ncRNA acvr2aa-002 (1) 539
    mRNA acvr2aa-203 (1) 5124
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM acvr2aa No data available
    MARKER RELATIONSHIPS
    acvr2aaContained in: [BAC] CH211-260F1 (1) (order this)
    acvr2aaEncodes: [EST] fa02e10
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001110278 (1) 3273bp
    Genomic GenBank:BX571777 (1) 155958bp
    Select Tool
    Polypeptide UniProtKB:F1R4D0 (1) 538aa
    Sequence Clusters UniGene:41373 (1)
    Sequence Information (all 24)
    OTHER acvr2aa GENE PAGES
  • Alliance (1)
  • Gene:553359 (1)
  • VEGA:OTTDARG00000020658 (1)
  • Ensembl(GRCz11):ENSDARG00000011188 (2)
  • ORTHOLOGY for acvr2aa (Chr: 9)
    CITATIONS (39)