ZFIN ID: ZDB-GENE-980526-123
Gene Name: Janus kinase 2b
Gene Symbol: jak2b
Sequence Ontology ID : SO:0000704

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Previous Name: Jak2b kinase

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(Including Attributions)
Location: Chr: 5 Mapping Details/Browsers
AUTOMATED DESCRIPTION
Predicted to have ATP binding activity, histone binding activity, and non-membrane spanning protein tyrosine kinase activity; predicted to be involved in intracellular signal transduction and protein  ...
GENE EXPRESSION
All Expression Data: 3 figures from 2 publications
Wild-type Stages, Structures: Pharyngula:Prim-5 (24.0h-30.0h) to Larval:Days 7-13 (168.0h-14d, 4.5mm, 8 teeth)
 
Curated Microarray Expression: GEO (1)
PHENOTYPE No data available
DISEASE ASSOCIATED WITH jak2b HUMAN ORTHOLOG
Disease Ontology Term OMIM Term OMIM Phenotype ID
acute myeloid leukemia Leukemia, acute myeloid, somatic 601626
Budd-Chiari syndrome {Budd-Chiari syndrome, somatic} 600880
essential thrombocythemia Thrombocythemia 3 614521
familial erythrocytosis 1 Erythrocytosis, somatic 133100
myelofibrosis Myelofibrosis, somatic 254450
polycythemia vera Polycythemia vera, somatic 263300
DISEASE ASSOCIATED WITH jak2b VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process intracellular signal transduction (more)
Cellular Component cytoskeleton (more)
Molecular Function ATP binding (more)
GO Terms (all 25)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000299 (1)
  • InterPro:IPR000719 (1)
  • InterPro:IPR000980 (1)
  • InterPro:IPR001245 (1)
  • InterPro:IPR008266 (1)
  • InterPro:IPR011009 (1)
  • InterPro:IPR016251 (1)
  • InterPro:IPR017441 (1)
  • InterPro:IPR019748 (1)
  • InterPro:IPR019749 (1)
  • InterPro:IPR020635 (1)
  • InterPro:IPR020693 (1)
  • InterPro:IPR035860 (1)
  • InterPro:IPR035963 (1)
  • InterPro:IPR036860 (1)
  • InterPro:IPR037838 (1)
  • InterPro:IPR041046 (1)
  • InterPro:IPR041155 (1)
  • InterPro:IPR041381 (1)
  • PROSITE:PS00107 (1)
  • PROSITE:PS00109 (1)
  • PROSITE:PS50001 (1)
  • PROSITE:PS50011 (1)
  • PROSITE:PS50057 (1)
  • Pfam:PF00017 (1)
  • Pfam:PF07714 (1)
  • Pfam:PF17887 (1)
  • Pfam:PF18377 (1)
  • Pfam:PF18379 (1)
  • EC:2.7.1.112 (1)
  • EC:2.7.10.2 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA jak2b-203 (1) 3389
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM jak2b No data available
    MARKER RELATIONSHIPSNo data available
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_131087 (1) 4536bp
    Genomic GenBank:CABZ01049033 (1) 19564bp
    Polypeptide UniProtKB:C0RW38 (1) 1126aa
    Sequence Clusters UniGene:81254 (1)
    Sequence Information (all 19)
    OTHER jak2b GENE PAGES
  • Alliance (1)
  • Gene:30298 (1)
  • VEGA:OTTDARG00000019129 (1)
  • Ensembl(GRCz11):ENSDARG00000018882 (2)
  • ORTHOLOGY for jak2b (Chr: 5)
    CITATIONS (29)