ZFIN ID: ZDB-GENE-980526-114
Gene Name: deltaB
Gene Symbol: dlb
Previous Names: deltab, etID309872.5 (1), sc:d0400
Location: Chr: 5 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 52 figures from 31 publications
Directly Submitted Expression Data: 6 figures (13 images) from Thisse et al., 2005 [eu57]
  7 figures (25 images) from Thisse et al., 2008 [cssl:d400]
Wild-type Stages, Structures: Gastrula:Shield (6.0h-8.0h) to Adult (90d-730d, breeding adult)
  adenohypophyseal placode, basal plate midbrain region, brain, caudal tuberculum (all 45) expand
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la015666Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la025026Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa1730 Point Mutation Unknown Unknown ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa16279 Point Mutation Unknown Unknown ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • European Zebrafish Resource Center (EZRC) (order this)
  • sa16283 Point Mutation Unknown Unknown ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • European Zebrafish Resource Center (EZRC) (order this)
  • sa16415 Point Mutation Unknown Unknown ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • European Zebrafish Resource Center (EZRC) (order this)
  • Targeting reagents: MO1-dlb (1), MO2-dlb (1), MO3-dlb (1)
    PHENOTYPE
    Data: Fig. 2 from Mizoguchi et al., 2011
    Observed in: posterior lateral line ganglion neuron
    DISEASE ASSOCIATED WITH dlb HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    spondylocostal dysostosis Spondylocostal dysostosis 1, autosomal recessive 277300
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process diencephalon development (more)
    Cellular Component integral component of membrane (more)
    Molecular Function calcium ion binding (more)
    GO Terms (all 10)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000152 (1)
  • InterPro:IPR000742 (1)
  • InterPro:IPR001774 (1)
  • InterPro:IPR001881 (1)
  • InterPro:IPR009030 (1)
  • InterPro:IPR013032 (1)
  • InterPro:IPR018097 (1)
  • PROSITE:PS00010 (1)
  • PROSITE:PS00022 (1)
  • PROSITE:PS01186 (1)
  • PROSITE:PS01187 (1)
  • PROSITE:PS50026 (1)
  • PROSITE:PS51051 (1)
  • Pfam:PF00008 (1)
  • Pfam:PF01414 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA dlb-001 (1) 3030
    ncRNA dlb-002 (1) 441
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYSNo data available
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM dlb No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    dlbContained in: [BAC] CH211-222C22 (1) (order this)
    dlbContains: [SNP] rs3727879 (1)
    dlbEncodes: [EST] eu57 (1)
    [cDNA] cssl:d400 (1) (order this), MGC:100773 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_130958 (1) 3007bp
    Genomic GenBank:BX005407 (1) 209796bp Blast at MegaBLAST
    Polypeptide UniProtKB:A0A0R4IYL5 (1) 616aa
    Sequence Clusters UniGene:574 (1)
    Sequence Information (all 17)
    OTHER dlb GENE PAGES
  • Gene:30141 (1)
  • VEGA:OTTDARG00000018419 (1)
  • Ensembl(GRCz10):ENSDARG00000004232 (1)
  • ORTHOLOGY for dlb (Chr: 5)
    Species Symbol Chromosome Accession # Evidence
    Human DLL3 19
  • Gene:10683
  • OMIM:602768
  • HGNC:2909
  • Amino acid sequence comparison (1)
    Conserved genome location (synteny) (1)
    Download Curated Orthology
    CITATIONS (84)