Gene

dlb

ID
ZDB-GENE-980526-114
Name
deltaB
Symbol
dlb Nomenclature History
Previous Names
  • deltab
  • etID309872.5 (1)
  • sc:d0400
Type
protein_coding_gene
Location
Chr: 5 Mapping Details/Browsers
Description
Predicted to have Notch binding activity. Involved in diencephalon development and midbrain development. Predicted to localize to plasma membrane. Is expressed in several structures, including adenohypophyseal placode; digestive system; ectoderm; nervous system; and neural plate. Human ortholog(s) of this gene implicated in dysostosis and spondylocostal dysostosis. Orthologous to human DLL1 (delta like canonical Notch ligand 1) and DLL3 (delta like canonical Notch ligand 3).
Genome Resources
Note
None
Expression
All Expression Data
55 figures from 33 publications
Cross-Species Comparison
High Throughput Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
Fig. 2 from Mizoguchi et al., 2011
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With dlb Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
spondylocostal dysostosis Alliance Spondylocostal dysostosis 1, autosomal recessive 277300
Associated With dlb Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR018097 EGF-like calcium-binding, conserved site
Domain IPR000742 EGF-like domain
Domain IPR001774 Delta/Serrate/lag-2 (DSL) protein
Domain IPR001881 EGF-like calcium-binding domain
Homologous_superfamily IPR009030 Growth factor receptor cysteine-rich domain superfamily
PTM IPR000152 EGF-type aspartate/asparagine hydroxylation site
Domain Details Per Protein
Protein Length Delta/Serrate/lag-2 (DSL) protein EGF-like calcium-binding, conserved site EGF-like calcium-binding domain EGF-like domain EGF-type aspartate/asparagine hydroxylation site Growth factor receptor cysteine-rich domain superfamily
UniProtKB:O57409 615
UniProtKB:Q1LYD2 615
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations