Gene

acvr2bb

ID
ZDB-GENE-170621-5
Name
activin A receptor type 2Bb
Symbol
acvr2bb Nomenclature History
Previous Names
None
Type
protein_coding_gene
Location
Unmapped
Description
Predicted to enable ATP binding activity; metal ion binding activity; and transmembrane receptor protein serine/threonine kinase activity. Predicted to act upstream of or within protein phosphorylation and transmembrane receptor protein serine/threonine kinase signaling pathway. Predicted to be located in membrane.
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With acvr2bb Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
visceral heterotaxy Alliance Heterotaxy, visceral, 4, autosomal 613751
Associated With acvr2bb Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Active_site IPR008271 Serine/threonine-protein kinase, active site
Domain IPR000472 Activin types I and II receptor domain
Domain IPR000719 Protein kinase domain
Family IPR000333 Ser/Thr protein kinase, TGFB receptor
Homologous_superfamily IPR011009 Protein kinase-like domain superfamily
Homologous_superfamily IPR045860 Snake toxin-like superfamily
Domain Details Per Protein
Protein Length Activin types I and II receptor domain Protein kinase domain Protein kinase-like domain superfamily Serine/threonine-protein kinase, active site Ser/Thr protein kinase, TGFB receptor Snake toxin-like superfamily
UniProtKB:A0A0G2KN81
Transcripts
Genome Browsers
No data available
No data available
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations