Gene

creld1b

ID

ZDB-GENE-161219-1

Name

CRELD disulfide isomerase 1b

Symbol

creld1b Nomenclature History

Previous Names

None

Type

protein_coding_gene

Location

Chr: 8 Mapping Details/Browsers

Description

Predicted to enable calcium ion binding activity and protein disulfide isomerase activity. Predicted to be located in membrane.

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

No data available

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With creld1b Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
		Atrioventricular septal defect, partial, with heterotaxy syndrome	606217
		Jeffries-Lakhani neurodevelopmental syndrome	620771
		{Atrioventricular septal defect, susceptibility to, 2}	606217

Associated With creld1b Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR018097	EGF-like calcium-binding, conserved site
Domain	IPR000742	EGF-like domain
Domain	IPR001881	EGF-like calcium-binding domain
Domain	IPR002049	Laminin-type EGF domain
Domain	IPR021852	Domain of unknown function DUF3456
Domain	IPR049883	NOTCH1 EGF-like calcium-binding domain
Family	IPR050751	Extracellular matrix structural protein
Homologous_superfamily	IPR009030	Growth factor receptor cysteine-rich domain superfamily
PTM	IPR000152	EGF-type aspartate/asparagine hydroxylation site
Repeat	IPR006212	Furin-like repeat

Domain Details Per Protein

Protein	Additional Resources	Length	Domain of unknown function DUF3456	EGF-like calcium-binding, conserved site	EGF-like calcium-binding domain	EGF-like domain	EGF-type aspartate/asparagine hydroxylation site	Extracellular matrix structural protein	Furin-like repeat	Growth factor receptor cysteine-rich domain superfamily	Laminin-type EGF domain	NOTCH1 EGF-like calcium-binding domain
UniProtKB:E7F4A7	InterPro
UniProtKB:A0A8M3AVN2	InterPro	400

Transcripts

Genome Browsers

NCBI

Type	Name	Annotation Method	Has Havana Data	Length (nt)	Analysis
mRNA	creld1-201 (1) Ensembl	Ensembl		1,221 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations