Gene

pkd1l2b

ID

ZDB-GENE-141222-87

Name

polycystic kidney disease 1 like 2b

Symbol

pkd1l2b Nomenclature History

Previous Names

pkd1l2
si:ch1073-128e6.1
si:ch211-168k15.4
si:ch211-168k15.5

Type

protein_coding_gene

Location

Chr: 7 Mapping Details/Browsers

Description

Predicted to have calcium channel activity. Predicted to be involved in detection of mechanical stimulus. Predicted to localize to membrane. Is expressed in amacrine cell; ceratobranchial cartilage; pharyngeal arch cartilage; pharynx; and retinal ganglion cell layer. Orthologous to human PKD1L2 (polycystin 1 like 2 (gene/pseudogene)).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

7 figures from England et al., 2017

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With pkd1l2b Human Ortholog

No data available

Associated With pkd1l2b Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR000203	GPS motif
Domain	IPR000922	D-galactoside/L-rhamnose binding SUEL lectin domain
Domain	IPR001024	PLAT/LH2 domain
Domain	IPR001304	C-type lectin-like
Domain	IPR013122	Polycystin cation channel, PKD1/PKD2
Domain	IPR042060	Polycystin-1 like, PLAT/LH2 domain
Domain	IPR046791	Polycystin domain
Family	IPR003915	Polycystic kidney disease type 2 protein
Homologous_superfamily	IPR016186	C-type lectin-like/link domain superfamily
Homologous_superfamily	IPR016187	C-type lectin fold
Homologous_superfamily	IPR036392	PLAT/LH2 domain superfamily
Homologous_superfamily	IPR043159	D-galactoside/L-rhamnose binding SUEL lectin domain superfamily
Homologous_superfamily	IPR046338	GAIN domain superfamily

Domain Details Per Protein

Protein	Length	C-type lectin fold	C-type lectin-like	C-type lectin-like/link domain superfamily	D-galactoside/L-rhamnose binding SUEL lectin domain	D-galactoside/L-rhamnose binding SUEL lectin domain superfamily	GAIN domain superfamily	GPS motif	PLAT/LH2 domain	PLAT/LH2 domain superfamily	Polycystic kidney disease type 2 protein	Polycystin-1 like, PLAT/LH2 domain	Polycystin cation channel, PKD1/PKD2	Polycystin domain
UniProtKB:E7F436 InterPro	124
UniProtKB:E7F2U9 InterPro	702

Transcripts

Genome Browsers

NCBI

Ensembl

ZFIN

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	pkd1l2b-201 (1) Ensembl	Havana	2597 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
mRNA	pkd1l2b-203 (1) Ensembl	Havana	3187 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
ncRNA	pkd1l2b-002 (1) Ensembl	Havana	892 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations