Gene
epob
- ID
- ZDB-GENE-141216-428
- Name
- erythropoietin b
- Symbol
- epob Nomenclature History
- Previous Names
-
- si:dkey-259i8.1 (1)
- Type
- protein_coding_gene
- Location
- Chr: 10 Mapping Details/Browsers
- Description
- Predicted to have erythropoietin receptor binding activity and hormone activity. Predicted to be involved in nucleate erythrocyte development. Predicted to localize to extracellular region and integral component of membrane. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); diabetic angiopathy; familial erythrocytosis 5; ischemia (multiple); and neurodegenerative disease (multiple). Orthologous to human EPO (erythropoietin).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from She et al., 2019
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 2 figures from She et al., 2019
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| familial erythrocytosis 5 | Alliance | Erythrocytosis, familial, 5 | 617907 |
| ?Diamond-Blackfan anemia-like | 617911 | ||
| {Microvascular complications of diabetes 2} | 612623 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Erythropoietin | Erythropoietin/thrombopoietin | Four-helical cytokine-like, core |
|---|---|---|---|---|
|
UniProtKB:A0A8M3AWM3
|
181 | |||
|
UniProtKB:A0A8M9QCG3
|
182 |
Interactions and Pathways
No data available
Plasmids
No data available