ZFIN ID: ZDB-GENE-141215-22
Gene Name: leiomodin 1b (smooth muscle)
Gene Symbol: lmod1b    Nomenclature History

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Previous Name: si:ch211-137o16.10

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 11 Mapping Details/Browsers
Description: Predicted to have actin binding activity and tropomyosin binding activity. Predicted to be involved in muscle contraction and pointed-end actin filament capping. Human ortholog(s) of this gene implicated in megacystis-microcolon-intestinal hypoperistalsis syndrome. Orthologous to human LMOD1 (leiomodin 1).
Genome Resources: Alliance (1),  Gene:795335 (1),  Ensembl(GRCz11):ENSDARG00000077261 (1)
GENE EXPRESSION
All Expression Data: Fig. 7 from Whitesell et al., 2019
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa35083 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH lmod1b HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH lmod1b VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process muscle contraction (more)
    Cellular Component cytoskeleton (more)
    Molecular Function actin binding (more)
    GO Terms (all 9)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA lmod1b-201 (1)    Ensembl 2715
    Browsers: NCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM lmod1b No data available
    MARKER RELATIONSHIPS
    lmod1b Contained in: [BAC] CH211-137O16 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:XM_001335460 (1)
    Genomic RefSeq:NW_018394821 (1) Blast at MegaBLAST
    Polypeptide UniProtKB:E7F062 (1) 671 aa
    Sequence Information (all 10)
    ORTHOLOGY for lmod1b ( Chr: 11 )
    CITATIONS (11)