Gene

si:dkey-172h23.2

ID
ZDB-GENE-141212-258
Name
si:dkey-172h23.2
Symbol
si:dkey-172h23.2 Nomenclature History
Previous Names
  • zgc:73349
Type
protein_coding_gene
Location
Chr: 7 Mapping Details/Browsers
Description
Predicted to enable MAP-kinase scaffold activity. Predicted to be involved in adrenergic receptor signaling pathway; positive regulation of I-kappaB kinase/NF-kappaB signaling; and regulation of Rho protein signal transduction. Predicted to act upstream of or within intracellular signal transduction. Predicted to be located in cytoplasm. Predicted to colocalize with actin cytoskeleton. Is expressed in cloaca; otic vesicle; pronephric duct; and sensory system. Orthologous to human AKAP13 (A-kinase anchoring protein 13).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
6 figures from Thisse et al., 2004
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With si:dkey-172h23.2 Human Ortholog
No data available
Associated With si:dkey-172h23.2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000219 Dbl homology (DH) domain
Domain IPR001849 Pleckstrin homology domain
Domain IPR002219 Protein kinase C-like, phorbol ester/diacylglycerol-binding domain
Domain IPR041020 ARHGEF1-like, PH domain
Family IPR028852 A-kinase anchor protein 13
Homologous_superfamily IPR011993 PH-like domain superfamily
Homologous_superfamily IPR035899 Dbl homology (DH) domain superfamily
Homologous_superfamily IPR036770 Ankyrin repeat-containing domain superfamily
Domain Details Per Protein
Protein Length A-kinase anchor protein 13 Ankyrin repeat-containing domain superfamily ARHGEF1-like, PH domain Dbl homology (DH) domain Dbl homology (DH) domain superfamily PH-like domain superfamily Pleckstrin homology domain Protein kinase C-like, phorbol ester/diacylglycerol-binding domain
UniProtKB:A0A2R8RR74 307
UniProtKB:F1RB67 1375
UniProtKB:A0A140LG29 2283
UniProtKB:A0A140LGK7 45
UniProtKB:A0A2R8Q302 213
UniProtKB:F1R7S0 942
UniProtKB:Q6PBL6 221
UniProtKB:A0A2R8QIH3 210
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Citations