Gene

magi2b

ID
ZDB-GENE-141211-6
Name
membrane associated guanylate kinase, WW and PDZ domain containing 2b
Symbol
magi2b Nomenclature History
Previous Names
  • si:ch211-127m7.3 (1)
Type
protein_coding_gene
Location
Chr: 25 Mapping Details/Browsers
Description
Predicted to localize to cell junction and plasma membrane. Human ortholog(s) of this gene implicated in nephrotic syndrome type 15. Orthologous to human MAGI2 (membrane associated guanylate kinase, WW and PDZ domain containing 2).
Genome Resources
Note
None
Expression
All Expression Data
1 figure from Jobst-Schwan et al., 2019
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With magi2b Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
nephrotic syndrome type 15 Alliance Nephrotic syndrome, type 15 617609
Associated With magi2b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR020590 Guanylate kinase, conserved site
Domain IPR001202 WW domain
Domain IPR001478 PDZ domain
Domain IPR008144 Guanylate kinase-like domain
Domain IPR008145 Guanylate kinase/L-type calcium channel beta subunit
Domain IPR041489 PDZ domain 6
Family IPR030036 Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2
Homologous_superfamily IPR027417 P-loop containing nucleoside triphosphate hydrolase
Homologous_superfamily IPR036020 WW domain superfamily
Homologous_superfamily IPR036034 PDZ superfamily
Domain Details Per Protein
Protein Length Guanylate kinase, conserved site Guanylate kinase-like domain Guanylate kinase/L-type calcium channel beta subunit Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 PDZ domain PDZ domain 6 PDZ superfamily P-loop containing nucleoside triphosphate hydrolase WW domain WW domain superfamily
UniProtKB:A0A2R8QA68 1300
UniProtKB:E7FH65 1332
UniProtKB:A0A0G2KGQ6 1149
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Gene Tree
Ensembl
Citations