ZFIN ID: ZDB-GENE-141210-1
Gene Name: MCC regulator of WNT signaling pathway
Gene Symbol: mcc
Sequence Ontology ID : SO:0000704

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Location: Chr: 5 Mapping Details/Browsers
Nomenclature History
Note: The Ensembl Zv9 mcc entry ENSDARG00000087450 lacks an ATG containing exon. 5'-RACE was performed. [Young et al (2014)] ENSDARG00000090139 contains sequence encoding the the N-terminal of the Mcc protein, which is missing in the ENSDARG00000087450 protein coding sequence.
GENE EXPRESSION
All Expression Data: 3 figures from Young et al., 2014
Wild-type Stages, Structures: Cleavage:2-cell (0.75h-1.0h) to Larval:Days 7-13 (168.0h-14d, 4.5mm, 8 teeth)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Targeting reagents:
PHENOTYPE
Data: 2 figures from Young et al., 2014
Observed in:
DISEASE ASSOCIATED WITH mcc HUMAN ORTHOLOG
Disease Ontology Term OMIM Term OMIM Phenotype ID
colorectal cancer Colorectal cancer, somatic 114500
DISEASE ASSOCIATED WITH mcc VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process convergent extension involved in gastrulation (more)
Molecular Function protein binding (more)
GO Terms (all 3)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR002048 (1)
  • InterPro:IPR011992 (1)
  • InterPro:IPR018247 (1)
  • InterPro:IPR019536 (1)
  • InterPro:IPR040171 (1)
  • PROSITE:PS00018 (1)
  • PROSITE:PS50222 (1)
  • Pfam:PF10506 (1)
  • Pfam:PF13499 (1)
  • TRANSCRIPTS No data available
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM mcc No data available
    MARKER RELATIONSHIPSNo data available
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:XM_021476718 (1)
    Genomic GenBank:FP245472 (1) 37718bp
    Select Tool
    Polypeptide UniProtKB:S5U9P9 (1) 1012aa
    Sequence Information (all 28)
    OTHER mcc GENE PAGES
  • Alliance (1)
  • Gene:100537329 (1)
  • Ensembl(GRCz11):ENSDARG00000105237 (1)
  • ORTHOLOGY for mcc (Chr: 5)
    CITATIONS (8)