ZFIN ID: ZDB-GENE-141006-1
Gene Name: solute carrier family 4 member 3
Gene Symbol: slc4a3    Nomenclature History

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Previous Name: Ae3 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 9 Mapping Details/Browsers
Description: Predicted to have inorganic anion exchanger activity. Involved in cardiac muscle cell action potential. Predicted to localize to integral component of membrane. Is expressed in fin and fin bud. Used to study short QT syndrome. Orthologous to human SLC4A3 (solute carrier family 4 member 3).
Genome Resources: Alliance (1),  Gene:100333073 (1),  Ensembl(GRCz11):ENSDARG00000104005 (1)
GENE EXPRESSION
All Expression Data: Fig. 3 from Shmukler et al., 2014
Wild-type Stages, Structures: Pharyngula:Prim-25 (36.0h-42.0h) to Larval:Protruding-mouth (72.0h-96.0h, 3.5mm)
 
High Throughput Expression: Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa34758 Point Mutation Unknown Unknown ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa34759 Point Mutation Unknown Unknown ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa41548 Point Mutation Unknown Unknown ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-slc4a3 N/A 1
    DISEASE ASSOCIATED WITH slc4a3 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH slc4a3 VIA EXPERIMENTAL MODELS
    Human Disease Fish Conditions Citations
    short QT syndrome AB + MO1-slc4a3 standard conditions Thorsen et al., 2017
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process cardiac muscle cell action potential (more)
    Cellular Component integral component of membrane (more)
    Molecular Function anion transmembrane transporter activity (more)
    GO Terms (all 9)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS No data available
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM slc4a3 No data available
    MARKER RELATIONSHIPS
    slc4a3 Contained in: [BAC] CH73-193I22
    [Fosmid] CH1073-395K13
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001302764 (1)
    Genomic GenBank:FP103057 (1) 87854 nt
    Select Tool
    Polypeptide UniProtKB:A0A096X8J7 (1) 1170 aa
    Sequence Information (all 22)
    ORTHOLOGY for slc4a3 ( Chr: 9 )
    CITATIONS (13)