Gene

pxdn

ID
ZDB-GENE-140415-2
Name
peroxidasin
Symbol
pxdn Nomenclature History
Previous Names
None
Type
protein_coding_gene
Location
Unmapped
Description
Predicted to have heme binding activity and peroxidase activity. Involved in basement membrane assembly.
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Fidler et al., 2014
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
1 Figure from Fidler et al., 2014
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With pxdn Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
anterior segment dysgenesis 7 Alliance Anterior segment dysgenesis 7, with sclerocornea 269400
Associated With pxdn Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000372 Leucine-rich repeat N-terminal domain
Domain IPR000483 Cysteine-rich flanking region, C-terminal
Domain IPR001007 VWFC domain
Domain IPR003598 Immunoglobulin subtype 2
Domain IPR003599 Immunoglobulin subtype
Domain IPR007110 Immunoglobulin-like domain
Domain IPR013098 Immunoglobulin I-set
Domain IPR034824 Peroxidasin, peroxidase domain
Family IPR019791 Haem peroxidase, animal-type
Family IPR034828 Peroxidasin, vertebrate
Homologous_superfamily IPR010255 Haem peroxidase superfamily
Homologous_superfamily IPR013783 Immunoglobulin-like fold
Homologous_superfamily IPR032675 Leucine-rich repeat domain superfamily
Homologous_superfamily IPR036179 Immunoglobulin-like domain superfamily
Homologous_superfamily IPR037120 Haem peroxidase domain superfamily, animal type
Repeat IPR001611 Leucine-rich repeat
Repeat IPR003591 Leucine-rich repeat, typical subtype
Domain Details Per Protein
Protein Length Cysteine-rich flanking region, C-terminal Haem peroxidase, animal-type Haem peroxidase domain superfamily, animal type Haem peroxidase superfamily Immunoglobulin I-set Immunoglobulin-like domain Immunoglobulin-like domain superfamily Immunoglobulin-like fold Immunoglobulin subtype Immunoglobulin subtype 2 Leucine-rich repeat Leucine-rich repeat domain superfamily Leucine-rich repeat N-terminal domain Leucine-rich repeat, typical subtype Peroxidasin, peroxidase domain Peroxidasin, vertebrate VWFC domain
UniProtKB:A0A0G2KHM6 1468
UniProtKB:A0A2R8QBP7 1457
UniProtKB:A0A2R8Q587 1440
UniProtKB:A0A2R8RMD9 319
UniProtKB:A0A2R8QDI7 1417
Transcripts
Genome Browsers
No data available
No data available
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations