ZFIN ID: ZDB-GENE-140129-1
Gene Name: transient receptor potential cation channel, subfamily C, member 3
Gene Symbol: trpc3    Nomenclature History

{{control.fieldName}} Edit

ID: {{control.nomenID}}
{{control.fieldName}}:
Reason:
Comments:

Attributions

{{pub.zdbID}}
Previous Name:

Add new Alias

Alias
Attribution

Attributions for Alias: {{control.newAlias}}

{{pub.zdbID}}

Delete Alias:

(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 14 Mapping Details/Browsers
Description: Predicted to have inositol 1,4,5 trisphosphate binding activity and store-operated calcium channel activity. Predicted to be involved in metal ion transport; regulation of cytosolic calcium ion concentration; and single fertilization. Predicted to localize to cation channel complex and integral component of plasma membrane. Is expressed in nervous system. Human ortholog(s) of this gene implicated in cerebellar ataxia type 41. Orthologous to human TRPC3 (transient receptor potential cation channel subfamily C member 3).
Genome Resources: Alliance (1),  Gene:101887082 (1),  Ensembl(GRCz11):ENSDARG00000098291 (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa40313 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH trpc3 HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    cerebellar ataxia type 41 Alliance ?Spinocerebellar ataxia 41 616410
    DISEASE ASSOCIATED WITH trpc3 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process calcium ion transmembrane transport (more)
    Cellular Component integral component of membrane (more)
    Molecular Function calcium channel activity (more)
    GO Terms (all 14)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA trpc3-201 (1)    Ensembl 1214
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM trpc3 No data available
    MARKER RELATIONSHIPS
    trpc3 Contained in: [BAC] CH73-370D1 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001289884 (1) 2518 nt
    Genomic GenBank:FP102983 (1) 91094 nt
    Select Tool
    Polypeptide UniProtKB:A0A0R4ISF6 (1) 902 aa
    Sequence Information (all 14)
    ORTHOLOGY for trpc3 ( Chr: 14 )
    CITATIONS (12)