Gene

elmo2

ID
ZDB-GENE-140106-84
Name
engulfment and cell motility 2
Symbol
elmo2 Nomenclature History
Previous Names
  • zmp:0000001124 (1)
Type
protein_coding_gene
Location
Chr: 11 Mapping Details/Browsers
Description
Predicted to have SH3 domain binding activity. Predicted to be involved in several processes, including apoptotic process; cell-cell adhesion; and phagocytosis. Predicted to localize to cytoplasm. Is expressed in brain; mid cerebral vein; and retinal ganglion cell layer. Orthologous to human ELMO2 (engulfment and cell motility 2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
3 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
4 figures from Boger et al., 2022
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With elmo2 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Vascular malformation, primary intraosseous 606893
Associated With elmo2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001849 Pleckstrin homology domain
Domain IPR006816 ELMO domain
Domain IPR024574 ELMO, armadillo-like helical domain
Homologous_superfamily IPR011989 Armadillo-like helical
Homologous_superfamily IPR011993 PH-like domain superfamily
Homologous_superfamily IPR016024 Armadillo-type fold
Domain Details Per Protein
Protein Length Armadillo-like helical Armadillo-type fold ELMO, armadillo-like helical domain ELMO domain PH-like domain superfamily Pleckstrin homology domain
UniProtKB:A0JMQ5 704
UniProtKB:A0A8M1NXH9 711
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Citations