Gene

sipa1

ID

ZDB-GENE-140106-128

Name

signal-induced proliferation-associated 1

Symbol

sipa1 Nomenclature History

Previous Names

zmp:0000001168 (1)

Type

protein_coding_gene

Location

Chr: 7 Mapping Details/Browsers

Description

Predicted to have GTPase activator activity. Predicted to be involved in several processes, including actin cytoskeleton reorganization; regulation of GTPase activity; and regulation of dendrite morphogenesis. Predicted to localize to integral component of membrane. Orthologous to human SIPA1 (signal-induced proliferation-associated 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

No data available

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With sipa1 Human Ortholog

No data available

Associated With sipa1 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR000331	Rap/Ran-GAP domain
Homologous_superfamily	IPR035974	Rap/Ran-GAP superfamily
Homologous_superfamily	IPR036034	PDZ superfamily

Domain Details Per Protein

Protein	Length	PDZ superfamily	Rap/Ran-GAP domain	Rap/Ran-GAP superfamily
UniProtKB:E7FFF0 InterPro	1261
UniProtKB:A0A8M9Q976 InterPro	1274
UniProtKB:A0A8M6YZL4 InterPro	1219
UniProtKB:A0A8M6Z7Y9 InterPro	1261

Transcripts

Genome Browsers: No data available

No data available

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance

Citations