Gene

msh4

ID

ZDB-GENE-131121-643

Name

mutS homolog 4

Symbol

msh4 Nomenclature History

Previous Names

None

Type

protein_coding_gene

Location

Chr: 17 Mapping Details/Browsers

Description

Predicted to have DNA-dependent ATPase activity. Predicted to be involved in resolution of meiotic recombination intermediates. Predicted to localize to synaptonemal complex. Orthologous to human MSH4 (mutS homolog 4).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

No data available

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With msh4 Human Ortholog

No data available

Associated With msh4 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR000432	DNA mismatch repair protein MutS, C-terminal
Domain	IPR007696	DNA mismatch repair protein MutS, core
Domain	IPR007860	DNA mismatch repair protein MutS, connector domain
Domain	IPR007861	DNA mismatch repair protein MutS, clamp
Family	IPR011184	DNA mismatch repair Msh2-type
Family	IPR045076	DNA mismatch repair MutS family
Homologous_superfamily	IPR027417	P-loop containing nucleoside triphosphate hydrolase
Homologous_superfamily	IPR036187	DNA mismatch repair protein MutS, core domain superfamily
Homologous_superfamily	IPR036678	MutS, connector domain superfamily

Domain Details Per Protein

Protein	Length	DNA mismatch repair Msh2-type	DNA mismatch repair MutS family	DNA mismatch repair protein MutS, clamp	DNA mismatch repair protein MutS, connector domain	DNA mismatch repair protein MutS, core	DNA mismatch repair protein MutS, core domain superfamily	DNA mismatch repair protein MutS, C-terminal	MutS, connector domain superfamily	P-loop containing nucleoside triphosphate hydrolase
UniProtKB:A0A8M3AK30 InterPro	800

Transcripts

Genome Browsers

NCBI

Ensembl

ZFIN

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	msh4-202 (1) Ensembl	Havana	541 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
mRNA	msh4-203 (1) Ensembl	Havana	3712 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations