Gene

aipl1

ID
ZDB-GENE-131121-577
Name
aryl hydrocarbon receptor interacting protein-like 1
Symbol
aipl1 Nomenclature History
Previous Names
  • aipl1a (1)
  • si:dkey-230a20.1
Type
protein_coding_gene
Location
Chr: 15 Mapping Details/Browsers
Description
Predicted to have peptidyl-prolyl cis-trans isomerase activity. Predicted to be involved in visual perception. Predicted to localize to cytoplasm and nucleus. Is expressed in brain; photoreceptor cell; retina; and retinal rod cell. Human ortholog(s) of this gene implicated in Leber congenital amaurosis; Leber congenital amaurosis 4; blindness; and retinitis pigmentosa. Orthologous to human AIPL1 (aryl hydrocarbon receptor interacting protein like 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
3 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With aipl1 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Leber congenital amaurosis 4 Alliance Cone-rod dystrophy 604393
Leber congenital amaurosis 4 Alliance Leber congenital amaurosis 4 604393
Leber congenital amaurosis 4 Alliance Retinitis pigmentosa, juvenile 604393
Associated With aipl1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain
Domain IPR013026 Tetratricopeptide repeat-containing domain
Family IPR031209 Aryl-hydrocarbon-interacting protein-like 1
Family IPR039663 AIP/AIPL1
Homologous_superfamily IPR011990 Tetratricopeptide-like helical domain superfamily
Repeat IPR019734 Tetratricopeptide repeat
Domain Details Per Protein
Protein Length AIP/AIPL1 Aryl-hydrocarbon-interacting protein-like 1 FKBP-type peptidyl-prolyl cis-trans isomerase domain Tetratricopeptide-like helical domain superfamily Tetratricopeptide repeat Tetratricopeptide repeat-containing domain
UniProtKB:A0A2R8QA37 156
UniProtKB:E7F4I7 462
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations