Gene

hs1bp3

ID

ZDB-GENE-131121-391

Name

HCLS1 binding protein 3

Symbol

hs1bp3 Nomenclature History

Previous Names

si:ch1073-80i24.2

Type

protein_coding_gene

Location

Chr: 17 Mapping Details/Browsers

Description

Predicted to have phosphatidylinositol binding activity. Involved in negative regulation of autophagy. Human ortholog(s) of this gene implicated in essential tremor 2. Orthologous to human HS1BP3 (HCLS1 binding protein 3).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

No data available

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: 1 Figure from Holland et al., 2016
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With hs1bp3 Human Ortholog

No data available

Associated With hs1bp3 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR001683	Phox homology
Domain	IPR037901	HCLS1-binding protein 3, PX domain
Family	IPR039701	HCLS1-binding protein 3
Homologous_superfamily	IPR036871	PX domain superfamily

Domain Details Per Protein

Protein	Length	HCLS1-binding protein 3	HCLS1-binding protein 3, PX domain	Phox homology	PX domain superfamily
UniProtKB:F6PCK0 InterPro	349
UniProtKB:Q6DHB3 InterPro	365

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	hs1bp3-201 (1) Ensembl	Havana	1589 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
ncRNA	hs1bp3-002 (1) Ensembl	Havana	687 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations