ZFIN ID: ZDB-GENE-131120-9
Gene Name: activin A receptor type 1Bb
Gene Symbol: acvr1bb    Nomenclature History

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Previous Names: sb:eu632, si:zfos-824d4.1 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 6 Mapping Details/Browsers
Description: Predicted to have activin binding activity and activin receptor activity, type I. Predicted to be involved in several processes, including activin receptor signaling pathway; cellular response to growth factor stimulus; and protein phosphorylation. Predicted to localize to activin receptor complex. Human ortholog(s) of this gene implicated in pancreatic cancer. Orthologous to human ACVR1B (activin A receptor type 1B).
Genome Resources: Alliance (1),  Ensembl(GRCz11):ENSDARG00000052142 (2)
GENE EXPRESSION
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2005 [eu632]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS No data available
PHENOTYPE No data available
DISEASE ASSOCIATED WITH acvr1bb HUMAN ORTHOLOG
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Pancreatic cancer, somatic
DISEASE ASSOCIATED WITH acvr1bb VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process phosphorylation (more)
Cellular Component integral component of membrane (more)
Molecular Function ATP binding (more)
GO Terms (all 20)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA acvr1bb-202 (1)    Ensembl 446
acvr1bb-203 (1)    Ensembl 1502
Browsers: NCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM acvr1bb No data available
MARKER RELATIONSHIPS
acvr1bb Contained in: [Fosmid] ZFOS-824D4 (1)
acvr1bb Encodes: [EST] eu632 (1)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
Genomic GenBank:CU929397 (1) 31256 nt
Select Tool
Polypeptide UniProtKB:F1QZF0 (1) 498 aa
Sequence Information (all 5)
ORTHOLOGY for acvr1bb ( Chr: 6 )
CITATIONS (15)