Gene
ptprjb.2
- ID
- ZDB-GENE-131120-137
- Name
- protein tyrosine phosphatase receptor type Jb, tandem duplicate 2
- Symbol
- ptprjb.2 Nomenclature History
- Previous Names
-
- si:dkey-5l8.2
- Type
- protein_coding_gene
- Location
- Chr: 25 Mapping Details/Browsers
- Description
- Predicted to enable protein tyrosine phosphatase activity. Predicted to be involved in axon guidance and signal transduction. Predicted to act upstream of or within protein dephosphorylation. Predicted to be located in plasma membrane. Human ortholog(s) of this gene implicated in colorectal cancer; lung adenocarcinoma; lung squamous cell carcinoma; and thrombocytopenia. Orthologous to human PTPRJ (protein tyrosine phosphatase receptor type J).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| colorectal cancer | Alliance | Colon cancer, somatic | 114500 |
| Thrombocytopenia 10 | 620484 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Active_site | IPR016130 | Protein-tyrosine phosphatase, active site |
| Domain | IPR000242 | Tyrosine-specific protein phosphatase, PTPase domain |
| Domain | IPR000387 | Tyrosine-specific protein phosphatases domain |
| Domain | IPR003595 | Protein-tyrosine phosphatase, catalytic |
| Family | IPR050713 | Receptor-type Tyrosine-protein Phosphatases/Ushers |
| Homologous_superfamily | IPR029021 | Protein-tyrosine phosphatase-like |
Domain Details Per Protein
| Protein | Additional Resources | Length | Protein-tyrosine phosphatase, active site | Protein-tyrosine phosphatase, catalytic | Protein-tyrosine phosphatase-like | Receptor-type Tyrosine-protein Phosphatases/Ushers | Tyrosine-specific protein phosphatase, PTPase domain | Tyrosine-specific protein phosphatases domain |
|---|---|---|---|---|---|---|---|---|
| UniProtKB:A0A8M9P6I8 | InterPro | 263 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
ptprjb.2-201
(1)
|
Ensembl | 1,042 nt |
Interactions and Pathways
No data available
Plasmids
No data available