ZFIN ID: ZDB-GENE-131119-33
Gene Name: si:zfos-411a11.2
Gene Symbol: si:zfos-411a11.2    Nomenclature History

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Previous Name: zmp:0000000718

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 15 Mapping Details/Browsers
Description: Predicted to have heme binding activity; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen; and steroid hydroxylase activity. Predicted to be involved in several processes, including exogenous drug catabolic process; organic acid metabolic process; and xenobiotic metabolic process. Predicted to localize to the cytoplasm and intracellular membrane-bounded organelle. Human ortholog(s) of this gene implicated in several diseases, including gastrointestinal system cancer (multiple); glucose metabolism disease (multiple); hematologic cancer (multiple); hypertension (multiple); and liver disease (multiple). Orthologous to several human genes including CYP2B6 (cytochrome P450 family 2 subfamily B member 6); CYP2C8 (cytochrome P450 family 2 subfamily C member 8); and CYP2F1 (cytochrome P450 family 2 subfamily F member 1).
Genome Resources: Alliance (1),  Gene:100000156 (1),  Ensembl(GRCz11):ENSDARG00000068493 (1)

Nomenclature Note: This gene is derived from the zebrafish genome sequencing and annotation project. When more is known about the gene, the current nomenclature will be replaced with more traditional zebrafish gene nomenclature. The prefix 'si:' indicates that this gene is represented by annotated genomic sequence from the Sanger Institute.

GENE EXPRESSION
Curated Microarray Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa10284 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa22559 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH si:zfos-411a11.2 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH si:zfos-411a11.2 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process oxidation-reduction process (more)
    GO Terms (all 1)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA cyp2y3-202 (1)    Ensembl 1596
    Browsers: NCBI
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM si:zfos-411a11.2 No data available
    MARKER RELATIONSHIPS
    si:zfos-411a11.2 Contained in: [Fosmid] ZFOS-411A11 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:XM_017351113 (1)
    Genomic GenBank:CU928854 (1) 39669 bp
    Select Tool
    Polypeptide RefSeq:XP_017206602 (1)
    Sequence Information (all 5)
    ORTHOLOGY for si:zfos-411a11.2 ( Chr: 15 )
    CITATIONS (11)