Gene

si:zfos-411a11.2

ID
ZDB-GENE-131119-33
Name
si:zfos-411a11.2
Symbol
si:zfos-411a11.2 Nomenclature History
Previous Names
  • zmp:0000000718
Type
protein_coding_gene
Location
Chr: 15 Mapping Details/Browsers
Description
Predicted to have heme binding activity; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen; and steroid hydroxylase activity. Predicted to be involved in several processes, including exogenous drug catabolic process; organic acid metabolic process; and xenobiotic metabolic process. Predicted to localize to cytoplasm and intracellular membrane-bounded organelle. Human ortholog(s) of this gene implicated in several diseases, including gastrointestinal system cancer (multiple); glucose metabolism disease (multiple); hematologic cancer (multiple); hypertension (multiple); and liver disease (multiple). Orthologous to several human genes including CYP2C8 (cytochrome P450 family 2 subfamily C member 8).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With si:zfos-411a11.2 Human Ortholog
No data available
Associated With si:zfos-411a11.2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR017972 Cytochrome P450, conserved site
Family IPR001128 Cytochrome P450
Family IPR002401 Cytochrome P450, E-class, group I
Family IPR008067 Cytochrome P450, E-class, group I, CYP2A-like
Homologous_superfamily IPR036396 Cytochrome P450 superfamily
Domain Details Per Protein
Protein Length Cytochrome P450 Cytochrome P450, conserved site Cytochrome P450, E-class, group I Cytochrome P450, E-class, group I, CYP2A-like Cytochrome P450 superfamily
UniProtKB:A0A8M6YUY2 491
Transcripts
Genome Browsers
Type Name Annotation Method Length (nt) Analysis
mRNA cyp2y3-202 (1) Havana 1596 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Citations