srpk2

ID

ZDB-GENE-131105-1

Name

SRSF protein kinase 2

Symbol

srpk2 Nomenclature History

Previous Names

si:zfos-332c3.3

Type

protein_coding_gene

Location

Chr: 25 Mapping Details/Browsers

Genome Assembly

GRCz12tu

Annotation Status

Current

Description

Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in intracellular signal transduction; regulation of mRNA processing; and spliceosomal complex assembly. Predicted to act upstream of or within protein phosphorylation. Predicted to be active in cytoplasm and nucleus. Orthologous to human SRPK2 (SRSF protein kinase 2).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

No data available

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: 1 Figure from Thyme et al., 2019
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With srpk2 Human Ortholog

No data available

Associated With srpk2 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Active_site	IPR008271	Serine/threonine-protein kinase, active site
Binding_site	IPR017441	Protein kinase, ATP binding site
Domain	IPR000719	Protein kinase domain
Family	IPR051334	Serine/Arginine-Rich Protein Kinases
Homologous_superfamily	IPR011009	Protein kinase-like domain superfamily

Domain Details Per Protein

Protein	Additional Resources	Length
UniProtKB:A0A8M9PV41	InterPro	693
UniProtKB:A0A8M3B6W8	InterPro	802
UniProtKB:A0A8M2BHX8	InterPro	802
UniProtKB:A0A8M9PYJ9	InterPro	817
UniProtKB:A0AB32TCG4	InterPro	771